Germfree is the preeminent company providing Class III Biological Safety Cabinets (BSC) in the USA. Class III (Glovebox) BSC lines have been a biosafety workhorse for many decades, serving the communities requiring up to BSL-4 containment and containment for operations generating pathogenic and toxin aerosols. These lines provide an important alternative to high construction and maintenance costs inherent in conducting work in a BSL-4 suite lab. When work involves dangerous pathogens or unknown agents, Class III BSC lines can be built to accommodate projects involving fermentors, processes that generate aerosols, and infected animals. Equipment such as incubators, autoclave, microscopes, refrigerators and analytical equipment can be contained. Design flexibility facilitates comfort and work flow, and provides effective and efficient alternatives to ingress, egress and decontamination processes.

Research-Aerobiology:

Germfree’s research and aerobiology Class III Biological Safety Cabinets are the standard for this emerging area of research. Originally co-developed with USAMRIID (United States Army Medical Research Institute of Infectious Diseases), these Class III BSCs provide a safe environment for performing aerobiology studies and can be equipped with a variety of accessories such as:

  • Rapid Transfer Ports (RTP)
  • Autoclaves
  • Airlocks
  • Dunk Tanks

These Class III BSCs can be designed for specific projects.

Animal Transfer:

Originally co-developed with USAMRIID (United States Army Medical Research Institute of Infectious Diseases), this innovative technology provides a new level of safety and efficiency for animal handlers, humane conditions and comfort for animals, as well as a rapid and continuous method of containment and transport for exposed and infected animals. The system greatly reduces human contact time with animals, the length of time the animal must be anesthetized, and the possibility of contaminating the environment. The transporters can dock to the Class III BSC or vivaria doors equipped with interlocking Rapid Transfer Ports (RTP), thereby eliminating containment breaches and potential animal injuries or escapes.

Hazardous Sample Receipt/Triage:

This Class III BSC designed for unique Laboratory Response Network (LRN) and Public Health Labs (PHL) triage requirements is both HEPA and ASZM-TEDA Carbon filtered to provide the highest level of user protection against chemical and biological threats. The Class III BSC provides an environment for the safe and secure containment, transportation and analysis of suspect NBC terrorism evidence from the facility receiving area to the analytical laboratory. The units can be fitted with Rapid Transfer Ports (RTPs) to facilitate chain of custody procedures, secure storage of Select Agents, and to simplify work flow and processing. This glovebox integrates with primary containment systems within the AHRF (All Hazard Receipt Facility). The technology for this glovebox was developed under a CRADA (Cooperative Research and Development Agreement) with the U.S. Army Edgewood Chemical and Biological Center.

Microbiology – SEA:

SAFE-ERGONOMIC-AFFORDABLE
At a fraction of the cost of standard Class III BSCs this glovebox provides an added level of safety in facilities that lack reliable secondary containment controls. This Class III BSC is part of a global solution to provide a safe, ergonomic and affordable (SEA) work environment during diagnostic screening of unknown and potentially highly pathogenic samples. Designed with the operator in mind, ergonomic considerations promote natural arm position, extend reach and reduced fatigue. The SEA makes efficient use of space and is easily cleaned and decontaminated. When lab space is at a premium, SEA is a sensible, cost effective solution for providing protection and separation of PCR reagents and sample preparation steps.

Portable and Mobile:

Portable and Movible Image

The standard Class III Portable Glovebox was developed by the U.S. Army specifically for handling WMD (Weapons of Mass Destruction) samples. This system is portable, transportable and rugged and is ideally suited for first responders. This Glovebox is a complete package with components and options developed, tested and field proven with over 300 units in mobile lab operation. The exhaust air filtration system is available with either HEPA or HEPA and Carbon (MIL Spec is available) filtration for either biological or chemical and biological hazards.

Rapid Containment for Field and Lab:

Rapid Containment Kit

The Rapid Containment Kit (RCK) provides a highly reliable, low cost, double HEPA or HEPA and Carbon filtered containment solution for field collection, laboratory containment, surge capacity, emergency response operations or as a decontamination chamber. It protects the user, the integrity of samples, reagents, and sensitive equipment from harsh environmental conditions and contaminants. The flexible film containment system is rapidly deployable and requires no tools for assembly. Low cost makes it a disposable unit.

Temperature and Humidity Control:

Temperature and Humidity Control

Germfree can provide Class III Biological Safety Cabinets with controls to maintain desired temperature and humidity within the enclosure. These gloveboxes are useful when performing studies in which environmental conditions are a critical factor.

Custom:

Custom

With a history of innovation, Germfree can solve your containment challenges. Let our designers and engineers work with you to provide the appropriate primary containment controls for your project.

 

Exhaust Filtration Systems:

Designed originally for military mobile laboratory applications, the NBC filter system unit has been incorporated into Class III BSC for civilian first responders and public health laboratories. Air coming from the Class III BSC passes through an exhaust HEPA filter prior to reaching the NBC Filter System Unit where it passes through an additional HEPA filter and two MIL Spec Carbon filters prior to discharge to the outside environment. The air sampling port located between the two Carbon filters is used to monitor any breakthrough from the first filter to determine whether both Carbon filters should be replaced during maintenance. Bubble-tight inlet and exhaust dampers allow for gas decontamination of the HEPA filter and housing prior to filter change. The filter unit is designed with a Bag-Out system for safe removal and disposal of the HEPA and Carbon filters.

Custom filtration systems are available.