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Monoclonal antibodies (mAbs) are copies of specifically designed antibodies designed to target specific antigens and associated diseases.  These immunotherapy treatments can be delivered through the bloodstream and trigger the immune system to destroy the cells containing the target antigen.

It is possible to create mAbs that are specific to almost any extracellular/cell surface target through these 4 materials/processes:

  • Murine: from mouse proteins with the names of the treatments ending in -omab.
  • Chimeric: part mouse and part human proteins with the names of the treatments ending in -ximab.
  • Humanized: small parts of mouse proteins attached to human proteins with the names of the treatments ending in -zumab
  • Human: fully human proteins with the names of the treatments ending in -umab.

Currently, mAbs therapies cover a wide range of treatments for cancer, rheumatoid arthritis, Crohn’s disease, HIV, multiple sclerosis, migraine headaches, Alzheimer’s disease, Ebola, and many other diseases.

Germfree’s bioGO® biocontainment cleanrooms are pre-designed and adaptive to provide an offsite built, process ready solution for advanced applications, available in 3 primary platform technologies:

Germfree’s advanced process and biosafety equipment is purpose built to meet client user requirements and includes:

·       Class II Biological Safety Cabinets

·       Cleanroom Pass-throughs

·       Laminar Flow Hoods

·       Restricted Access Barrier Systems (RABS)

·       Aseptic Isolators

·       Dehumidification Chambers

·        Cleanroom Tables, Shelves, and Workstations 

Speak with an Expert today to learn more about how Germfree can amplify your process.

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Robust Experience

Germfree consistently delivers exceptional Biopharma compliant products around the globe. Browse the grid below to see a selection of relevant past projects:

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