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US Biocontainment Manufacturer Delivers Mobile Unit for Work on Coronavirus Vaccine

ORMOND BEACH, Fla. and LOUISVILLE, Ky., April 9, 2020 /PRNewswire/ — This week, Germfree delivered a 53-foot containment cleanroom trailer to a major US pharmaceutical company where they will work on a COVID-19 vaccine. This is the first, of what is expected to be, many mobile laboratory spaces that will be delivered to scientists and organizations working on virus and antibody testing, vaccine development, research, and deployment solutions. Germfree was quickly able to meet the need for a biocontainment unit specifically designed for COVID-19 vaccine development because the company has decades of experience providing rapidly deployable biocontainment laboratory space. Since the 1990s, the Germfree has pioneered the use of mobile containment cleanrooms for surge capacity, hospital renovations, and emergency preparedness. In recent years, the company has deployed over 60 mobile solutions like the ones needed to meet the COVID-19 crisis to public and private healthcare systems across the US, including to the National Institutes of Health (NIH), Massachusetts General Hospital, Stanford Health Care, Kaiser Permanente, UW Medicine, Yale New Haven Health, and the US Department of Veterans Affairs (VA).

This experience positions Germfree to provide what is needed today as well as solutions that can be easily tailored in the future to meet needs that have yet to be identified.

“While not endorsing any particular company or product, rapidly deployable, complete laboratories will greatly enhance the US response to testing for COVID-19.” said Paul Jensen, Ph.D., Lead for Infection Control and Biosafety at the Centers for Disease Control and Prevention (CDC), upon commenting on flexible solutions and laboratory safety.

Just as scientists and healthcare professionals have pivoted to focus efforts on reducing the lethality of COVID-19, Germfree employees and the company’s supply chains have coordinated to be ready to provide researchers and healthcare systems with what they need to fight this virus. Germfree’s well-trained workforce is incredibly versatile and has years of experience providing scientists and the healthcare industry with precisely what they need when they need it. With an Essential Critical Infrastructure Workforce designation from the Department of Homeland Security and procedures in place to protect the health of employees, Germfree remains ready to produce.

Over the years, Germfree has developed strong relationships with vendors, assuring a continuous supply chain for production. Some, such as Kentucky Trailer, a key provider of specialty mobile platforms, are prioritizing Germfree so that the company can quickly meet the needs in the field:

“We clearly understand the importance of Germfree’s mobile labs in the national response to COVID-19. Early on, we worked together to put a plan in place to prioritize critical production demands and maintain supply chain resiliency during these unprecedented circumstances,” said Tom Harper, a VP at Kentucky Trailer.

“As an essential critical infrastructure business, Kentucky Trailer and our dedicated associates are honored to assist Germfree in the fight against the COVID-19 pandemic,” added Gary A. Smith, Sr., President and CEO of Kentucky Trailer. “What we make matters, underscored by the importance in the combined effort of two great companies partnering to address this historic, must-win challenge.”

Other manufacturers have stepped up to formalize plans to provide Germfree with components:

“We put extra mechanisms in place to avert disruptions and secure the supply chain for Germfree during the pandemic,” said Tim Confer, President, Northern Air Systems, a provider of specialty cooling units for the mobile laboratories.

The U.S. Department of Health and Human Services (HHS) has designated Germfree and its employees as ‘Essential Mission Infrastructure Support’. Together, with its collaborating vendors, Germfree will continue to employ Americans to provide scientists and healthcare systems with the critical biocontainment capacity they need to save lives and win the fight against this virus. Germfree and its partners are essential to the mission of national health security.

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High Containment Laboratory used for COVID-19 research. Shows interior of offsite-constructed facility built by Germfree Labs in its US factory and installed in Singapore. Duke-NUS researchers were among the first to culture the SARS-CoV-2 and begin study on COVID-19.

Ormond Beach, FL, US – April 1st, 2020 – By mid-March, the emerging pandemic sounded alarms at the highest levels and Germfree was being asked to provide biological containment laboratories – fast. Calls came in from public health labs and researchers across the globe who work to contain local outbreaks and prevent regional epidemics. Now facing a pandemic, priorities shifted, and efforts intensified as did the need for bio-containment space. The global response to COVID-19 would reveal critical deficiencies in global laboratory capacity that now require fast, flexible solutions.


“COVID-19 presents unprecedented challenges to our global laboratory infrastructure,” said Dr. Steven Jones, Associate Provost for Health Sciences at the University of Saskatchewan and co-discoverer of a vaccine for Ebola. Jones has confronted these concerns with previous coronavirus outbreaks. “Our laboratory capabilities must be agile and responsive to potential biological threats in a wide range of scenarios. In 2014, I worked with Germfree to quickly deploy one of their laboratories to the Middle East to deal with MERS, which was very similar to the current pandemic virus.”

High Containment Laboratory used for COVID-19 research. Shows exterior of offsite-constructed facility in Germfree’s US factory prior to shipment and installation in Singapore. Duke-NUS researchers were among the first to culture the SARS-CoV-2 and begin study on COVID-19.


Germfree-built facilities are in operation across the world, from resource-challenged regions to modern cities, including a high containment lab in Singapore at the forefront of COVID-19 research: “Duke-NUS was one of the first few laboratories in the world to culture the SARS-CoV-2 and since then we have been working on various aspects of the outbreak,” said Dr. Viji Vijayan, Associate Dean – Research Operations, Safety and Central Procurement at Duke-NUS.


“Building the labs that are crucial to Global Health Security – this is what we do. It is our responsibility to apply all our resources to assist with the pandemic at this time. Germfree is quickly adding factory capacity to build this essential infrastructure as well as offering expertise to industry partners who are trying to fulfill the unmet need,” said Kevin Kyle, President of Germfree. “While our mission is intact, the pandemic created a seismic shift of the landscape in which we all now operate. We quickly pivoted to focus our resources on those serving in the trenches of this terrible pandemic.”

BSL-3 Biological Containment Laboratory; Keith Landy, CEO of Germfree, Tom Frieden, Former CDC Director. The BSL-3 (Biosafety Level 3) laboratory was manufactured by Germfree Labs in their US factory and then shipped and installed in Zaria, Nigeria. This created a new method to augment lab infrastructure and support global public health security anywhere in the world. These labs serve as outposts for disease surveillance with the goal of containing emerging threats.


In the 1990’s, Germfree pioneered the manufacture of mobile and modular, high containment laboratories. Germfree has since further refined designs and developed the capability to rapidly deploy facilities to any region of the world, creating a new model for disease surveillance in remote areas. “Everything that Germfree has done over the last 20 years has prepared us to contribute solutions to this type of situation,” said Keith Landy, CEO of Germfree. “I first started working with the US Army to develop equipment and mobile facilities that could address biological threats and those have evolved into all of the platforms we now use to deliver offsite-built containment labs. Germfree has over a hundred laboratory installations and has deployed the most advanced Biosafety Level 3+ labs on the planet,” continued Landy. “These installations are designed to operate in harsh conditions and remain sustainable in remote regions of the world. I think this deep-rooted experience and expertise combined with our history of global deployments has prepared Germfree to solve some of the very complex challenges that we must confront during this pandemic and for future preparedness.”


“It is vital that we have sufficient global lab capacity for the outbreaks we’ve seen, but more importantly, for the ones we must predict,” added Dr. Steven Jones.

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For full quotes and high resolution images please see out Press backgrounder.

Pass-Through Chambers for the Modern Pharmacy Cleanroom

Germfree has leveraged our decades of facility design experience to develop a pass-through (airlock) that is uniquely engineered to meet the demands of a modern pharmacy cleanroom. All stainless steel construction with coved interior and exterior corners and a pharmaceutical grade finish make these pass-through boxes the most cleanable and robust on the market.

Germfree’s line of Cleanroom Pass-Through Boxes are designed to facilitate the safe transfer of materials between work areas within a pharmacy cleanroom. Sealed pass-through boxes maintain complete environmental separation between work areas. The pass-through box air eliminates cross contamination between work areas during both material ingress and egress.


Application:
For use in hospital pharmacy and pharmaceutical cleanrooms to maintain control of particulates as materials are passed from one room to another. Pass-through boxes reduce traffic within the cleanroom while expediting the transfer of product, supplies and equipment. These units are deigned to fit seamlessly into both new and existing cleanroom facilities.
Per USP <800>: “…a method to transport HDs, HD CSPs, and HD waste into and out of the negative pressure buffer room to minimize the spread of HD contamination. This may be accomplished by use of a pass-through chamber between the negative-pressure buffer area and adjacent space. The pass-through chamber must be included in the facility’s certification to ensure that particles are not compromising the air quality of the negative-pressure buffer room.”

Standard Features:

  • HEPA Purge and Static Pass-Through models available
  • All stainless steel construction
    • Fabricated from the most robust materials, Germfree’s cleanroom pass-through boxes are designed to withstand the repeated use and daily cleaning required by a cleanroom facility
  • Coved interior and exterior corners
    • These units are designed to be highly cleanable, both inside and out
  • Gas-tight Construction
  • Supply and Exhaust HEPA Filters
  • HEPA Purge
    • HEPA Purge Models Only – When materials are placed within the pass-through box and the doors are closed, a HEPA-purge cycle is initiated which rapidly exhausts and filters the interior air until it has reached ISO Class 7
  • Mechanical interlocks
    • This system prevents both doors from ever being opened simultaneously
    • HEPA Purge Models Only – The receiving side door will remain locked for the duration of the purge cycle
  • Windows
    • Viewing windows allow a clear line of site both within the pass-through box and between rooms


Optional Features
:

  • Sliding tray in the work area
  • Gas Decontamination Port
  • Inflatable Gasket Seals

Voltage Options:

  • System requires 110V, 60Hz, 20-amp hard-wired power connection (230V, 50Hz system available)
  • Optional wall plug

Standard Sizes (Internal Dimensions*):

24” x 24” x 24”
16” x 24”x 24”
16” x 16” x 24

*Applies to HEPA Purge and Static Pass-Through models

2 April 2019

Ardmac and Germfree are pleased to announce the launch of their partnership to bring Germfree bioGO Mobile and Modular Cleanroom Buildings to the European markets.

Germfree provides a fully adaptable Cleanroom solution that supports manufacturing for pre-clinical or clinical stage materials in a single or multiple-module Cleanroom building. Once scale up or scale out needs are identified, additional modules can be added seamlessly. As well, a mobile solution can be used and then upgraded into a modular platform to provide the fastest implementation of Pre-clinical and early Phase discovery.

The Germfree bioGO Cleanroom Solution adapts with your business needs by optimizing your company’s time to market and return on investment.

Ronan Quinn CEO of the Ardmac Group and Kevin Kyle, President of Germfree
Ronan Quinn, CEO of the Ardmac Group and Kevin Kyle, President of Germfree

Following agreement at Germfree’s facility in Ormond Beach, Florida Ronan Quinn CEO of the Ardmac Group stated “I am delighted to conclude two years of discussions with Germfree and add this highly engineered solution to complement our already significant modular offering. There is a high demand from both our existing customers in the Biologics market and those in the advanced therapy medicinal products (ATMPs) for modular offsite built process ready facilities.”

Kevin Kyle, President of Germfree stated “The Germfree Team is thrilled to find the right partner in Ardmac such that we can deliver added value and enable the cures of the future. This partnership brings together two companies strong in innovation and client focused solutions. The combination of our bioGO Mobile Cleanroom Trailers and Modular Cleanroom Buildings provides a unique solution for Biotech applications that will help solve the shortage of usable manufacturing space.”

Established in 1977 and Headquartered in Dublin, Ireland, Ardmac is an international construction company that delivers high value workspaces and technical environments.

Germfree, established in 1962 and Headquartered in Ormond Beach, Florida is a global company working to create environments that serve life science innovation and advance global health.

To read more about Ardmac Cleanrooms, Click HERE

December 8 – 12, 2019 – Las Vegas, NV

The American Society of Hospital Pharmacists Midyear Clinical Meeting, aimed at bringing together pharmacy industry professionals, will convene in Las Vegas, Nevada in December 2019. There will be opportunities for networking, sharing knowledge, and experiencing the latest technologies.

October 28 – 30, 2019 – Kansas City, MO

The Health Connect Partners Reverse Expo Fall will take place in Kansas City, Missouri in October 2019. Hospital Pharmacy Directors from America’s most prestigious hospitals and health systems will come together with industry leaders in the Pharmacy Manufacturing and Technology sectors to network and share ideas.

October 27 – 31, 2019 – Las Vegas, NV

Professionals of all levels in the Pharmaceutical and manufacturing fields will gather for the 2019 International Society for Pharmaceutical Engineering Annual conference in Las Vegas, Nevada in October. This event will offer biopharmaceutical professionals a chance to share ideas and information about new developments and technology.

September 18, 2019 – Foxboro, MA

The International Society for Pharmaceutical Engineering Boston Annual meeting being held in Boston, MA in September 2019 promises to bring together a broad range of industry leaders in the BioPharma Manufacturing fields. There will be opportunity for educational enrichment, as well as networking and experiencing the latest in biopharmaceutical technology.

July 14 – 17, 2019 – Baltimore, MD

Join a wide range of industry leaders in the pharmacy and health care fields at the American Society for Healthcare Engineering Annual Conference and Technical Exhibition in Baltimore, Maryland in July 2019. The conference provides opportunities for networking and idea exchanges, as well as a glimpse into the industry for startups.

June 3 – 6, 2019 – Philadelphia, PA

This year’s BIO international convention will bring together industry leaders is the biotechnology and biopharmaceutical fields. This is a good opportunity for startups and larger companies to experience the Tri-state area.

May 16, 2019 – Philadelphia, PA

The 29th annual International Society for Pharmaceutical Engineering Delaware Valley Chapter symposium and exhibition is an opportunity for leaders in the Life Science industry can come together to share information and ideas. The event will feature: prestigious keynote speakers, vendor exhibits, as well as education and career clinics.

May 6 – 8, 2019 – Miami, FL

The Health Connect Partners Spring Reverse Expo is an innovative twist on the traditional event as the providers man exhibit booths, while the suppliers walk the floor. This will take place in Miami, Florida, May 6-8, 2019.

April 10 – 12, 2019 – Oxon Hill, MD

The World Orphan Drug Congress will gather in Maryland in April 2019 to bring together industry leaders from all reaches of the BioPharma and Biotechnology industry to share information and ideas on this important topic.

April 2 – 4, 2019 – New York, NY

INTERPHEX is an annual event for pharmaceutical, biotechnology, manufacturing and device development. This conference is based in New York, NY and will take place in April 2019.

April 1 – 4, 2019 – Dublin, Ireland

The 2019 ISPE Europe Annual Conference will take place in Dublin, Ireland from April, 2019. The conference will “focus on four core areas that continue to drive, challenge, and shape pharma manufacturing and Facilities of the Future with a focus on innovation in facilities and production”

March 18 – 19, 2019

Bethesda, MDThe 2019 International Society for Pharmaceutical Engineering Aseptic Conference will be held in Bethesda, Maryland. This year the conference will focus on multi-product facilities, and increasing use of robotics as they relate to the future of aseptic processing.

February 22, 2019 – Tampa, FL

Moffitt Cancer Center Annual Conference will be held in Tampa, Florida on February 22, 2016. This year’s conference will be called Business of Biotech 2019 – Cracking the Cancer Code.

September 26, 2018 – Foxboro, MA

The International Society for Pharmaceutical Engineering will hold their Boston Product Show in Foxboro, Massachusetts on September 26, 2018. This show provides attendees the opportunity to experience the top new technology in the pharmaceutical industry from leading industry providers.

May 10, 2018 – Alachua, FL

BioFlorida is hosting their outdoor industry celebration in Alachua, Florida on May 10, 2018. This event will include exhibits, networking opportunities, music and food as well as offering bus tours of the local biotechnology community.

April 30-May 2, 2018 – Atlanta, GA

The Hospital Pharmacy Conference will take place in Atlanta, Georgia on April 30-May 2, 2018. This conference will provide educational and networking opportunities as well as a reverse expo.

April 23-26, 2018 – Phoenix, AZ

The National Home Infusion Association will hold their annual conference in Phoenix, Arizona on April 23-26, 2018. The Conference provides an opportunity for education and networking for executives, clinicians and professionals involved with the home infusion industry.

April 17-19, 2018 – New York, NY

The 2018 INTERPHEX will take place in The Javits Center in New York, NY on April 17-19, 2018. This event brings together driven professionals with pharmaceutical and biotechnology industry leaders for valuable information and knowledge sharing.

March 19-21, 2018 – Orlando, FL

Parenteral Drug Association (PDA), will hold it’s annual meeting in Orlando, Florida on March 19-21. This meeting will cover the wide scope of the future of pharmaceutical manufacturing.

March 13, 2018 – Raleigh, NC

The conference will encourage strategic partnerships, sourcing new technology and developing best practices by engaging with the biotechnology and pharmaceutical industries.

March 11-13, 2018 – Hilton Head, SC

Topics ranging from updates to USP 797/USP 800 to advanced pharmacy practices will be covered in three different educational tracks.

March 6-7, 2018 – Reston, VA

The International Society for Pharmaceutical Engineering (ISPE) will hold its ISPE Aseptic Conference in Reston, Virginia on March 6-7, 2018.

February 20-22, 2018 – Bethesda, MD

The International Society for Pharmaceutical Engineering (ISPE) will hold its conference ISPE Facilities of the Future: Innovating the Future of Manufacturing in Bethesda, Maryland on February 20-22.

February 10-14, 2018 – Atlanta, GA

Presented By: Centers for Disease Control and Prevention (CDC) in partnership with the Eagleson Institute and the American Biological Safety Association (ABSA International)

Germfree presents a truly unique approach to bringing advanced high containment laboratories to wherever they are needed anywhere in the world.

Germfree designs, engineers and manufactures biological safety level three laboratories in our U.S. facility. These containerized modular labs are then delivered and installed in locations across all continents.

After manufacture the lab is transported as containerized units to be reassembled at the site. This method makes easy global deployment a new possibility for high containment labs.

BSL-3 labs require a range of critical steps after completion of construction and prior to laboratory operation. These processes traditionally take six months to over a year. This Germfree project took just twenty one days from on-site setup to meeting all operational requirements, making the BSL-3 lab ready for use.

With Germfree’s advances in biosafety engineering and manufacturing, high containment laboratories can now become operational in an unprecedented timeframe.

Thank you for purchasing Germfree’s Laminar Flow Glovebox Isolator, the LFGI. With this purchase you have started down the road to making your pharmacy a safer environment for both your personnel and your patients. Before you begin it is important to fully understand the operation of the LFGI and its features.

In this video we will walk you through the entire process, from installation to everyday usage. In the future you can use the menu options to review specific sections of this video for reference during training. Now let’s begin.

It is important that users of the LFGI have a basic knowledge of how the unit works. There are a few basic principles that will help users gain a better understanding of the unit, and contribute to its safe and effective usage for years to come.

Your Laminar Flow Glovebox Isolator is so named because it utilizes Laminar, or Unidirectional flow. What this means is that all air that enters the work area is passed through a HEPA filter before it enters the work area. This air is then drawn through the work area in a single pass, knocking and removing particulates in the air as it goes. Unidirectional air flow provides the work area with the highest possible level of protection because it does not allow particulates to build up, a state that may lead to cross contamination.

Another important concept to understand is pressurization. Your LFGI has been configured at the factory to run under either positive or negative pressure. The pressurization of the LFGI simply refers to the difference in pressure between the work area and the surrounding room.

When the pressure of the work area is greater than that of the surrounding room the unit is said to be under positive pressure. You will notice that the glove sleeves are being pushed out of the unit. What means is that if there is a breach of containment, such as a tear in the glove were to occur, the air in the work area will be pushed out of the unit, providing protection for whatever product was being manipulated. You can see here that even with the sleeve completely removed, the room air is unable to enter the work area. Positive pressure is ideal when working with non-hazardous compounds and when product protection is of the highest importance.

Conversely, when the room pressure is greater than that of the work area, the LFGI is said to be under negative pressure. You will notice that the glove sleeves are being sucked into the work area. In this instance, if containment were lost because of a rip or tear, room air would be sucked into the work area at a rate that would prohibit any air from exiting the unit. Negative pressure is ideal when working with hazardous drugs and in all situations where personnel protection has been deemed to be of paramount importance.

For more complete explanations of Laminar Flow and positive and negative pressure, please consult the LFGI user’s manual. Now let’s get familiar with the product.

The HEPA purge airlock or antechamber allows materials to be easily brought into or taken out of the unit without transferring the room air to the work area or vice versa. Two HEPA filters inside the airlock change out the air during a purge cycle. The purge cycle can be activated by pressing the purge button located on the control panel. Also on the control panel you will find controls to turn the unit on and off, and to control the lights. The control panel also contains a mini helix gauge and a digital pressure gauge. For a full explanation of the LFGI’s gauges and their purpose, consult your owner’s manual.

The LFGI features anthropometrically correct glove ports. These glove ports, originally developed by NASA, have been designed to allow for the greatest possible range of motion for users of all body types.

Opening the airlock from the inside of the unit, you will find a sliding tray designed to facilitate easy transfer of materials into and out of the LFGI.

The unit also contains sliding trays in the work area. These trays make movement within the isolator easier and more efficient. Additionally, these trays can be moved or removed during cleaning to allow you full access to the work area. Trash and sharps tubes, located on the side of the unit, allow the user to easily pass waste out of the LFGI without disrupting workflow.

Your Laminar Flow Glovebox Isolator comes with a height adjustable stand which allows users of different heights to work easily within the unit. A motorized stand is available as an option.

Once you have installed your LFGI and have had it certified you are almost ready to begin use. Please consult your LFGI’s operator manual for detailed information on installation and certification.

To begin, make sure your LFGI is plugged into a functioning outlet. Now it is the time to install the glove sleeves. Regardless of the sleeve type you are using, the sleeve should wrap easily around the outside of the glove ports. Once the sleeve is in place, secure it by using the O-ring clamp.

If you are using a two part glove sleeve, you can attach any commercially available glove. To do this, first pull the sleeve out of the box so that the sleeve is inside out. place the glove over sleeve, or GOS, over the sleeve, and roll the sleeve so it just covers the GOS.

Now, take the O-ring clamp and place it over the sleeve, making sure that it settles into the GOS groove furthest from you.

Often, stretching the glove with both hands will help loosen it and make the job easier. Additionally, this will allow you to check for any defects in the glove. Take the glove and place it inside the sleeve, making sure the thumb is pointed upwards. Now, take the glove and roll the cuff over the sleeve and GOS. Take the second O-ring and place it over the the glove securing it into the GOS groove closest to you.

After the sleeves and gloves have been installed they should be visually inspected for any cuts or tears. When the unit is under pressure the unit’s low-flow alarm will sound if containment has been compromised. You can now push the entire sleeve and glove back into the box.

This procedure can be followed for all glove changes during standard maintenance, however there are procedures for changing a glove during an operation and we will deal with that later in the video.

Next, open the viewing panel. Inspect under the work tray to ensure that there is nothing below the sliding trays, and remove any fallen objects that you find. You will then clean the airlock by opening the interior airlock door and sliding the tray into the work area. Now, open the outer airlock door and quickly spray the floor of the airlock with disinfectant cleaner and wipe down.

Spray a clean wipe with disinfectant cleaner and wipe the top HEPA filter protector from front to back, left to right with overlapping strokes. Now, repeat this procedure on the back HEPA filter.

Repeat this procedure on the inside of the airlock doors and on all sides.

Slide the airlock tray back into the airlock and close the interior door.

Finally, spray the cleaner on the tray and wipe it down in the same manner.

Close the airlock and make sure both doors are latched.

At this point, it is time to clean the interior of the unit. To perform this task, you will need a water-based, hight pH disinfectant cleaner as well as 70% alcohol solution. Because this is the initial cleaning, we will open the front window. If your LFGI is operated under negative pressure you should never open this front window until a thorough cleaning has been performed with the window closed. In this event, all of the procedures that I will describe can be followed, but must take place through the gloves. Germfree can provide you with an isolator cleaning tool to assist you. For more information, please consult your LFGI’s operator’s manual.

To begin, spray disinfectant cleaner on a lint free cleaning wipe. Wipe the filter diffuser on the top of the work area, wiping from side to side, overlapping strokes. Work outward from back to front.

Spray the back wall of the work area. Wipe the wall beginning at the top and wipe top to bottom using overlapping strokes working downwards toward the work surface, and wipe the rear air return grille. Work sideways from left to right.

Repeat the same procedure for the sidewalls.

Slide the left tray over the right tray. Spray the interior bottom surface of the isolator. Clean by wiping from the back to the front using overlapping strokes. Be sure to clean the side and back under the sliding work tray air return grille. Do not spray cleaners directly at the exhaust HEPA filter. Always spray the cleaners onto the cleaning wipe and then clean the protector surface.

Slide both work trays to the left, and repeat the procedure on the right side. Sliding work trays are removable if preferred.

Spray the sliding work tray and wipe using a side to side motion, overlapping strokes, working from back to front, and clean all inside and outside edges.

Remove glove sleeves and spray the inside of the front access window.

Using overlapping strokes, clean from top to bottom. Remember this must be done through the gloves in a negative pressure unit.

Spray a clean wipe with disinfectant cleaner and use it to clean the glove ports.

Spray a clean wipe with disinfectant cleaner and use it to clean the IV hanging bar and hooks.

Spray a clean wipe with disinfectant cleaner and use it to clean the front air return grille.

Spray and wipe the gloves and sleeves.

After cleaning, replace the gloves and glove sleeves.

Spray a clean wipe with 70% IPA and wipe the supply HEPA diffuser in the top of the work area. The supply HEPA diffuser should never be sprayed directly to avoid damage to the filter.

Spray 70% IPA directly on all surfaces of the rest of the work area. Close the front access window, clamp, and allow to dry for 10 minutes. After the the 10 minutes has elapsed, ensure that the stoppers for the trash and sharps are seated in place. If the viewing panel is open, close it. If you want to you can lock the wind at this time.

Now you are going to clean the outside of the unit. The outside can be cleaned at any time while the unit is closed. This procedure does not require that you wear additional personnel protection equipment beyond what you would normally wear when working inside the LFGI. The stainless steel should be cleaned with a 70% alcohol solution, or one that is specifically designed for the cleaning of stainless steel. the acrylic front and side panels should be cleaned with a soft cloth and mild detergent or a solution that’s specifically designed for the cleaning of acrylic. It is important to never use abrasive cleaners or organic solvents on the acrylic. Also, the acrylic should never be cleaned with a solution stronger than 50% ethyl or 70% isopropyl alcohol. Do not use glass cleaner that contains ammonia.

Work from top to bottom. Do not remove or spray the pre filter at the top of the unit.

When cleaning the airlock HEPA filter housings, do not spray directly onto the airlock, rather spray the solution into a cloth and then wipe the outside surface. Raise the adjustable stand at least three inches and wipe down the caster supports.

Never spray any type of cleaner directly at the control panel located above the airlock. Always spray onto a clean wipe and then wipe the surface switches and knobs. Now, make sure the pre filter is seated properly in its frame at the top of the unit. You should not see it above the steel frame. Turn on the work area light, and watch for its operation.

Turn on the main blower switch. The low pressure alarm will sound until adequate pressure is achieved. If the unit is under positive pressure, the gloves will push out of the work area, under negative pressure they will pull into the work area. Push the airlock purge button and make sure that the accompanying red light turns on.

Now, you are ready to work inside the LFGI. For safe and efficient use of the Laminar Flow Glovebox Isolator, you should take into account the equipment and materials necessary for the preposed operation and list the procedural details for each operation. The best way to accomplish this is through the use of a checklist or protocol that includes all equipment, apparatus, tools, products and supplies necessary for each specific procedure. the list should include the order of events in enough detail to successfully carry out the proposed operation. This list needs to be exhaustive including such items as initial cleaning equipment, spill control equipment and even extra gloves in case a change is required in the middle of an operation. It is recommended to perform several trial runs in the Laminar Flow Glovebox Isolator before initiating preparation.

If you are using teach and waste containers, make sure they are attached properly. The trash bag should be secured to the tube by the clamp. If you are using the optional trash container, the bag should fit down into the container.

The sharps container can either be brought into the work area or it can be placed on the side of the unit. In this case the sharps collector shelf should be adjusted so that the sharps tube fits down into the container. This setup is recommended for positive pressure use only.

Now, adjust the stand to a comfortable working height. Wipe down the materials that you will be bringing into the LFGI and place these materials inside the airlock. Push the airlock button, the red light will turn on. Do not open the airlock door until the red light is turned off. The factory has set the purge time at one minute.

Working through the gloves, open the airlock door and slide the work tray out. Remove the items from the tray and slide the tray back into the airlock. Close and lock the airlock door. Now you are ready to begin preparation.

Remember, any waste created can be disposed of through the waste and sharps tubes, however when you are not using the tubes the rubber stoppers should remain in place to assure containment.

During the course of your normal work inside the LFGI, it is possible that you may rip or tar a glove or sleeve. In this event you can easily change out that glove or sleeve without breaking containment. To change a sleeve or glove while maintaining containment, first pull the glove and sleeve outside of the work area so that they are inside out and remove the glove O-ring. roll the existing glove’s cuff down to the first groove of the GOS, the one that is closest to your body.

Now pick a new glove and stuff it inside the existing glove, leaving the cuff out and making sure that the thumb is pointed upwards. Stretch the new glove’s cuff up and over the old one up to the middle groove of the GOS. Secure the new glove with the O-ring at the middle groove of the GOS. Push the glove and sleeve back into the work area. Reach into the work area through another glove and grab the new glove assembly. With two fingers, carefully work the old glove up off the GOS from inside the work area. Dispose of the old glove through the waste tubes, and push a hand into the new glove.

If you were to tear a sleeve during operation. this can also be replaced without breaking containment. First remove the O-rind and move the sleeve to the outermost glove port for you. Push the new sleeve inside of the old one and pull the new sleeve over the glove port down to the innermost groove. Replace the sleeve O-ring to secure the new sleeve. Reach inside the work area with another glove and pull the sleeve off and into the work area. Dispose of the old sleeve through the airlock or trash tubes.

That’s it! You’re up and running in your new LFGI. Now each time you use the unit you must follow the procedures in the following order.

First, inspect the gloves and sleeves to make sure that they are free of any rips or tears.

Clean the inside of the airlock.

Make sure that both airlock doors are latched.

Place your sharps container either on the side of the unit, or inside.

Attach the waste container.

Clean in inside of the work area. Remember, you should not open the view window if you are under negative pressure.

Make sure the stoppers for the trash and sharps tubes are in place. Turn on the work area light. Turn on the main blower switch and allow the unit to pressurize.

Push the airlock purge button and make sure the red light activates. Allow 10 minutes to pass in order to make sure that the work area is filtered numerous times and reaches an ISO class 5 condition.

Adjust the stand to a comfortable height.

Wipe down and place compounding elements in the airlock.

Press the airlock purge button and wait for the red light to turn off. The purge has been factory set at one minute. Once the light is off, open the interior airlock door and remove the compounding elements. Close the airlock door.

Begin preparation.

Dispose of waste and sharps through the trash tubes, remembering to always replace the rubber stoppers. Remove the completed preparation through the airlock.

Please use this training video as a resource to stay informed on the safe use of the LFGI. More detailed information can be found in your LFGI operator’s manual. Remember the Laminar Flow Glovebox Isolator is a tool to aid the operator in maintaining a clean environment for the compounding of preparations. It is not a substitute for proper aseptic technique. We at Germfree believe that the proper use of our equipment will create a safer environment for patients and pharmacists for years to come.

It is important that users of the Versaflow have a basic knowledge of several principles that will enable them to safely and effectively use this equipment for years to come. This video will cover two topics: Laminar flow and positive pressure. Let’s begin with laminar flow.

The Versaflow utilizes laminar, or unidirectional airflow to prevent cross contamination. All of the air inside a Versaflow passes through a HEPA filter before it enters the work area. The HEPA filter cleans the air by removing airborne contamination, such as dust, pollen and droplets that can harbor spores, bacteria and viruses. This downdraft of clean air flows from top to bottom and prevents airborne particulates from building up, minimizes the likelihood of cross-contamination and provides the highest level of protection possible. Your Versaflow utilizes positive air pressure to control any contamination that may be present inside the work area.

Positive pressure describes when the air pressure inside the Versaflow is higher than the air pressure in the room. When the air inside the Versaflow is under positive pressure you can see that air is being pushed out. If a breach of containment, such as a tear in the glove, were to occur when there is positive pressure inside the Versaflow, the air inside the unit would flow outward. The outward flow of HEPA filtered air would provide protection for the product inside the Versaflow by keeping contaminated air in the room from coming into the work area. You can see that even with a sleeve completely removed, the room air is unable to enter the Versaflow. Positive pressure is ideal when working with non hazardous compounds and when product protection is of the highest importance. Based on the chemical properties of the products that will be made inside your Versaflow. Positive pressure can be utilized to maximize patient safety and product protection.

For more information, or to speak with a technical representative at Germfree, call 1-800-888-5357, or go to www.germfree.com

I’d like to welcome you today to Germfree Laboratories’ Mobile USP 797 compliant cleanroom. We’d like to just take a few minutes to walk you through the facility so that you can see many of the same features that you’re used to in your facility’s cleanroom today, however just in a compact environment. If you can imagine fitting everything you have inside your hospital inside a 53 foot trailer, that’s what we’ve done and we want to show you how you can maintain operability while renovating your existing facility.

Once again a fully compliant USP 797 facility which allows you to move your operation from the hospital into this facility, continue uninterrupted while you bring your facility up to the current standards.

Now lets go over some of the things we’ve included in this operation that we have, this mobile pharmacy cleanroom. We’re standing now in the entry room or the office are, so as you come through the entry door, which is just over here behind the camera where he’s standing now. You’ll come into this area where the pharmacists will be stationed. We have two different desks, or work areas set up, and similar to what we have in all of the cleanroom applications, we have stainless steel furniture that’s set up. It’s very cleanable. It’s very smooth, so that when you have personal protective equipment on and you’re wiping this down, it allows for a good cleanable surface to work with. Let’s talk about the walls of the facility. The walls are made up a material that’s referred to as Arcoplast, which is a very cleanable compound. It’s not permeable to any type of object that would get through it and stick so in order to keep your contamination levels down, or your sterility, this is a premium product. The walls are then sealed up into the ceiling grid as well as into the other walls and doors. The floor material that we have is a Medintech laboratory medical grade flooring, similar to what you have seen in your hospital set up. Its heat welded seams and coved up the walls, again you have a non permeable floor to work with.

We have two separate rooms in this mobile pharmacy. We have a hazardous drug buffer room and on the other end we have a non-hazardous drug buffer room. So, the hazardous drug room is running at a negative pressure, in order to do your chemotherapy compounding. Obviously the positive pressure room for all of the normal sterile compounding of your IVs.

In order to pass things in and out of the buffer rooms from the office area, or the entry, we have a pass-box. This pass-box also has a HEPA filtered purge system, so any particle count that could be in the air here in the office will be cleaned out by that HEPA filtered purge before it’s passed into your positive pressure buffer room.

This office area is maintained in ISO 8 conditions at its very worst, but you’ll see in the ceiling we have HEPA filtered ventilation with fan filter units. We also have low wall returns, so this area is bathed with a constant filtered air supply with many air changes per hour going on in here in order to clean the air constantly.

Also, some of the features that we have in the facility for enhanced security and monitoring of what’s going on in the exterior as well as the interior, we have a CCTV, or a camera system, which also is recorded on a DVR, so from the exterior security standpoint you are able to monitor what’s going on 24 hours a day, 7 days a week, and record if anything were to occur, as well as with cameras that are inside the mobile pharmacy.

Now, for communications we have an intercom system. That intercom system allows you to communicate in multiple different ways. You can communicate from the exterior door outside, into the entry area, you can also communicate into the positive pressure buffer room or the hazardous drug buffer room. Additionally, for security purposes, we have an alarm system. The alarm system monitors the entry door, the emergency exit door that’s in the negative pressure room, as well as the door on the mechanical space which is on the back of this particular trailer.

The entry door is controlled in two fashions: one by a standard key deadbolt and the other by a combination lock so that easy access can be gained with the combination lock for your personnel entering the facility during the day. When you want to secure it at night, simply lock the deadbolt with a key tip of a lock to provide more security.

Once again here in the entry room we’ve got our ceiling grid is made up of a cleanroom grade typical ceiling grid, however we have ruggedized it to be substantially stronger than what you may find in the normal cleanroom. For the sake of this being a mobile, so it can handle the rigors of being on the highway to come to your facility and then be set up and still be in place.

The lighting that’s in place is a T5 fluorescent light so we have a nice bright light as you can see in this room to aid your workers in doing their work accurately. In the event that there’s a loss of power, in each individual room there is emergency lighting ballast, so the room will still be well lit to provide any necessary exit that might occur while the loss of power is going on. Additionally with the loss of power, we’ve also backed up the mobile cleanroom with a generator. So the generator is capable to one of the two air conditioners, all of the fan filter units and exhaust blowers, the biosafety cabinets that are used for the chemo compounding, as well as the positive pressure vertical airflow units that are used in the sterol compounding area, and the refrigerators. So all of your operations can continue in a safe fashion. All off your drugs will still be refrigerated, all of your pressures will be maintained, all of the cabinets will still be working. So not only will your technicians be still protected, but as well as the drugs that they are particularly compounding at the time will still be protected. So we’ve pretty well covered everything that we have in the entry room. We can now go on into our change room, or anteroom that we have.

Okay, as we enter into the anteroom, going into the hazardous drug buffer room, we have magna helix on the wall to verify that the proper pressure is maintained as you go into the room. So you can see that we have +.03 inches of positive pressure in the room, so we know that there’s clean air leaking out of there. We’re safe to go into the anteroom, the room.

Now for the purpose of the demonstration, we’ve propped the door open to the anteroom, but obviously it would be self-closing with the door-closer on. So, we come into the anteroom. If it’s necessary to sit down to put on outer covers over the shoes, we have a fold down bench here on the wall. Makes it convenient to get up and out of the way or to use if necessary. Obviously a key component to what’s going on here is we have a hand washing sink. So we have heated water to be able to wash your hands. In addition we have an emergency eyewash station here if there was a need for an eyewash. Soap dispenser, towel dispenser on the wall. Additionally we have small shelving up here to house the PPE that’s necessary for donning before going into the hazardous drug room. As we come in through the next room, obviously this door would be shut, we can again verify on the pressure gauge on the wall that we have the correct negative differential pressure across this door. So we can now verify before we go into the room that our negative pressure there is desired, it’s safe to go into the room, we can go into the negative pressure room.

Okay, so now we are here in the negative pressure room where the hazardous drugs are compounded. You can probably hear more of the airflow that’s going on because we have our biosafety cabinets operating. We have the thimble with the exhaust operating. So everything that’s functioning in here to maintain the room in it’s safe condition is operational at this point. You probably also can tell that the sound level is actually relatively low. So with the amount of airflow that’s here that’s required, it’s still a comfortable working environment. I’ll point out a few things that we have in the back of our mobile pharmacy cleanroom. We have an emergency exit door that’s provided. We always feel that that’s essential in a mobile application like this. If there were an emergency that were blocking the entry door, whether it’s inside or outside, a person can open the door and they can safely get out and not be trapped inside. And then of course, the heart of all of this, we come back to our Class II A2 Biosafety Cabinets which, of course, are Germfree equipment installed. All stainless steel. Stainless steel work deck. This is the premier equipment for doing your hazardous drug compounding. In addition to the other cabinet that we have, we also have a rolling workstation here. So, the necessary equipment can be put on these shelves. We don’t have them in place right now, but they’er in addition to these fixed shelves that are on this cart. We have several places for adjustable shelves. This ends up having a total of five shelves when it’s all said and done.

Over here next to the biosafety cabinet then, we have our cleanroom compliant refrigerator, glass door, wire racks inside. It has alarms for a high temperature situation. Also has a chart recording so that you can always verify that the temperature has been maintained. You can always verify that the drugs have been maintained at the right temperature.

And then again just around the corner we have another shelving unit, just a little smaller than the first. Again it has fixed shelves and additionally will have adjustable shelves on there.

As we were in the entry room, we talked about having an intercom system. So, here is the intercom that interfaces with our hazardous drug room to any of the other rooms. Now when a call is placed from the entry room into here, so if the pharmacist wants to talk to the technician that’s back, they will have to push a button to activate the call. However once it’s activated the technicians that are in this room functioning can communicate hands free. So, when they have their sterile gloves on there’s actually no need for them to touch a button if the call was initiated from outside.

Additionally, we talked about security cameras, both only do we have the monitor in the entry room for the security cameras, but it’s also monitored back here. Above the monitor, we also have the camera that’s monitoring this room. for the safety and security, as well as making sure that technical accuracy is upheld within the room.

As we come back into this area, we come to the opposite of our pass through box. So again, when it’s necessary to pass a tray of sterile drugs out, they can be placed in here. Once the door is shut, it activates the purge. The lights indicating now, I don’t know if you can hear it, but there is a faint sound from the blower running, which is actually circulating air through here, through the HEPA filters, to remove any contaminates from the air as they’re passed through.

Also in this hallway, we have a work surface where any writing can be done to take notes, documentation of what’s happening with the drugs as they’re passed out. Again, like all of the furniture that we have, this is stainless steel, it’s coved, it’s seamless. So again, very cleanable, easy to maintain, and not a place for really any contaminates to permeate the surface.

In this wall, also we have both of our air conditioner thermostats. These are set up to maintain the correct temperature that you need in the cleanroom. With the amount of personal protective equipment required to be worn, always necessary to keep a cool environment so that your technicians are comfortable. This will easily maintain a sixty-eight degree environment. So, they are very comfortable in their working situation.

We’ve now exited the negative buffer room, or the hazardous drug room. We’re back into the entry, and we’re about to go into the positive pressure buffer room. So once again, before we go into the anteroom, we have a pressure gauge here indicating that we have the right positive differential pressure across that, indicating it’s safe for us to go through this door and into the anteroom.

We’re now in the anteroom for the positive pressure buffer room. As we look around, here we see all of the same features that we found in the other anteroom. We have the fold down seats that aid in donning the PPE footwear, the shelving, the sink. Everything is identical in here, with the exception of the fact that we have a small step up in because we’re now going into a slightly higher elevation in this mobile facility, which is actually on a trailer platform. So, as we are now coming into the positive pressure room, again we have a gauge indicating that we have a safe positive pressure, differential pressure, across this door. It’s now safe for us to go through and into the positive pressure buffer room.

We’ve now come into the positive pressure buffer room. There’s a lot of things going on up here with shelving and workstations. The Germfree equipment.

I want to talk about some of the airflow and the air quality conditions in here. The airflow in all of the rooms is coming in from the top through the fan filter units. Coming down across the floor and then exiting through low wall returns. There are return grills all the way across the front wall of this providing for a nice directional airflow that’s happening in this buffer room.

Again, where all of the business is occurring in this buffer room is in the Germfree equipment up here. This is a vertical laminar flow workstation. A new design that Germfree has just implemented, where the blowers are actually underneath and directing airflow from underneath and then bathing the work surface in that HEPA filtered air whine the compounding is occurring.

Again, we have the workstations like you saw before. These have outlets on the backsplash for any equipment that might be set here. The adjustable shelves that can be set at different heights to accommodate different heights of equipment you may have. And now again, we have a shelving unit similar to what we looked at in the negative pressure buffer room. However these do already have installed their adjustable shelves. So you can see, there’s actually a very large amount of storage that’s afforded here. Again, a lot of adjustability, and the shelf heights. And if you can see this here, we’ve actually got a coved lip, so if anything were to be spilled on these smaller shelves it would all be contained right here within that surface.

With the workstation that we have, not only do we have this countertop surface and the adjustable shelves, but we also have a rolling bin cart. So, it’s very easy for the operators to now take this bin cart, set it aside. They can put any tools that they’re working with, they can put their particular bins of supplies and have it as a ready access. It’s also convenient then to simply store that backing out of the way, and not waste any floor space in the room.

And again, in the positive pressure buffer room we have the laboratory and pharmacy approved refrigerator. It has the adjustable shelves inside, which again are a wire rack. Temperature alarm, indicating that you have a high temperature or a low temperature in the refrigerator. As well as the strip chart recorder, again to verify that everything in the contents of the refrigerator have been maintained at the proper temperature.

Also, in this corner, which is very similar to the negative pressure buffer room, we have the pass box, which allows for the passing of the compounded drugs into. Place the tray in the door. Shut the door. The blower starts, allows for the purge, once again, then you can pass out without exchanging any particles between rooms.

Again, you have another work surface that’s here. Stainless steel, coved, seamless, just like all of the other furniture in the facility.

Another important safety feature that we have in this room, and every room of the facility, is a combination smoke detector as well as a carbon monoxide detector. Everyone understands the smoke detector, however, because this is a mobile facility with a generator onboard, it’s really important to have the detection for carbon monoxide. In the very unlikely event that exhaust gasses were to somehow leak into the facility, this would alarm alerting that it was necessary for the technicians to safely evacuate until the conditions corrected.

Up on this front wall of the room, we have the security camera for monitoring what’s going on in this particular room, as well as the monitor, which mimics what’s being displayed in the entry room as well as in the negative pressure buffer room. And then we have the intercom, which allows for communication once again between the entry and the other buffer room, or here and the front entry door. And notice that we have clear windows here, as well as here, and down below. This provides for great visibility between the entry room and the positive pressure buffer room, as well as back in the negative pressure room. Great visibility between the office and these spaces, so it’s very easy for the pharmacist to monitor what the technicians are doing. It’s very easy to see from one room or the other what’s going on, and provides for greater visual cues as well as the voice communications that can happen.

We’re back in the entry office area again and some things to point out. When we’ve passed sterile drugs out of the positive pressure buffer room, we have another work bench area here, and a place to set a tray down, also a place to record data that’s necessary with the transfer of those drugs. And then down underneath, an access door where we have our plumbing connections. So we have a fresh water tank, a gray water tank, as well as fresh water pump in order to provide a supply of water to the two sinks in the anterooms as well as then handle the waste from that and collect that onboard.

Some of the more control type features that we have here in the entry. We have a combination panel here, which monitors out 12 volts. We have two batteries onboard: one that’s operating for our pump and things in the laboratory, and another that’s for the start for the generator. The breakers that also operate courtesy lights, water pump. And then we have a control panel for our generator that’s onboard. As well as a fuel level indication. And then we have a tank monitor indication for our fresh and gray tanks. So, for example, when I push the fresh tank, it provides the read-out in a percentage indicating to me that I have seventy-nine percent full on the fresh water tank.

The panels that we have here are the breaker panels, which provide the AC power distribution throughout the mobile pharmacy cleanroom. This panel is the one that maintains all the essential loads and is backed up by our generator. This panel is the less essential loads such as, some of the miscellaneous outlet power, tank heaters, and things of that nature.

I want to thank you for taking the time to watch this video. It’s really important for Germfree Laboratories to be able to express to our potential customer base what the potential uses are for this facility. You may have the need to renovate your cleanroom in your facility, and it’s necessary to not shut down your compounding, but have the ability to move over and seamlessly transition right into this facility. To provide a short-term rental solution and not interrupt the flow of drugs that you need. So once again, thank you for taking the time to watch this video.

Germfree provides advanced turnkey mobile compounding pharmacies.
These units are equipped to handle all the compounding operations that are conducted in traditional buildings.
Facility renovations present unique challenges to the hospital pharmacy.
During construction, compounding services can not be interrupted.
It is also critical to maintain all standards for safety in aseptic conditions.
Germfree presents an innovative solution to sustain compounding services during any disruption to your facility.
These mobile units are also ideal for surge capacity or emergency preparedness.
The pharmacy is designed with distinct work zones.
Each environment maximizes safety, sterility and optimal workflow.
The Hazardous Drug Preparation area is an ISO 7 environment, operating under negative pressure.
The room is equipped with Class II biological safety cabinets.
The Sterile Compounding room is also ISO 7, but operates under positive pressure.
This zone is equipped with laminar flow workstations.
The pharmacy has an ISO 7 Anteroom for each compounding zone.
These serve as changing areas for personnel.
The office area is also maintained as a controlled environment.
HEPA purge Pass-throughs allow for efficient transfer of compounded preparations. Security and communications systems are provided throughout the mobile unit.
The pharmacy interior is constructed of premium materials selected for durability and ease of cleaning. The unit features stainless steel work surfaces and fixtures, with ample storage.
Dual redundant AC systems enhance user comfort.
A backup generator ensures that power is never interrupted for all critical systems.
Germfree’s Mobile Compounding Pharmacies are delivered to your site whenever they are needed.
They provide the ideal solution to seamlessly maintain all compounding operations.

Germfree presents it’s line of 100% stainless steel Pharmacy equipment.
The BTE Series biological safety cabinet
The BZ Series horizontal laminar flow workstation
The BBF Series biological safety cabinet
The Versaflow compounding aseptic isolator
The BV Series vertical laminar flow workstation
The LFGI Series compounding aseptic isolator
and the Radiopharmacy Series nuclear isolator
Which like all our models features a unidirectional air flow system that maintains ISO class 5 and class 100 HEPA air quality under dynamic conditions.
All products meet requirements for USP 797 compliance.
We also offer a full line of accessories designed to enhance your product experience.
Be sure to ask about our total customer care extended warranty program and our mobile pharmacy line.
Germfree protecting patients, personnel and products for over 45 years.

We offer a comprehensive range of cleanroom facilities for sterile and hazardous drug operations. Configurations are available for integration with existing buildings, free-standing pharmacies and full 503B compounding centers. Our single-source solution provides a complete pharmacy with all standard equipment. Germfree handles all aspects of your new cleanroom — delivered and made operational in a truncated timeline.

December 4-6, 2017 – San Francisco, CA

The International Society For Pharmaceutical Engineering will host its biopharmaceutical manufacturing conference in San Francisco, California from December 4-6th, 2017.

December 3-7, 2017, Orlando, FL

The American Society of Health-System Pharmacists will hold their midyear clinical meeting and expo in Orlando, Florida from December 3-7th, 2017.

October 29 – November 1, 2017 – San Diego, CA

The International Society for Pharmaceutical Engineering will host its annual meeting and expo in San Diego, California on October 29 – November 1st, 2017.

October 26-29, 2017 – Las Vegas, NV

The California Society of Health-System Pharmacists will hold their annual seminar from October 26-29th, 2017 in Las Vegas, Nevada.

October 26-28, 2017 – Portland, OR

The Veterinary Cancer Society will convene its annual conference in Portland, Oregon form October 26-18th 2017.

October 16 – 18, 2017 – Chicago, IL

The Hospital Pharmacy Conference will convene in Chicago, Illinois from October 16-18th, 2017.

October 15-17, 2017 – St. Petersburg, FL

The 20th annual BIOFLORIDA Conference will take place in St. Petersburg, Florida from October 15-17th, 2017.

October 13-18, 2017 – Albuquerque, NM

The American Biological Safety Association will convene its 60th annual international conference in Albuquerque, New Mexico from October 13-18th, 2017.

October 11-14, 2017 – Guadalajara, Mexico

The 48th Union World Conference on Lung Health – Accelerating Towards Elimination will take place in Guadalajara, Mexico from October 11-14th, 2017.