Barrier Isolators play a critical role in a range of processes. Barrier Isolators are commonly used for research and to facilitate a proper environment for sterile compounding in the hospital pharmacy and cleanroom, these units provide both an aseptic work area as well as safety for personnel. Barrier Isolators are commonly utilized for compounding sterile preparations (or CSPs).
Biological safety cabinets are an enclosed, ventilated hood or workspace that allow for safely handling pathogens, contaminants or other potentially hazardous materials.
This type of equipment is also referred to as biosafety cabinets or microbiological safety cabinets. When outfitted with glove systems (in the case of Class III biosafety cabinets), they are also called gloveboxes. There are various classes of biological safety cabinets, each defined by the required level of biosafety and containment as well as the required configuration of the cabinetry.
Biological safety laboratories are designed and equipped to safely handle pathogens and other potentially hazardous materials. These facilities vary widely in the type and degree of risk of the materials being handled. Sometimes these labs are constructed and operated for a specific application that will define the required Biological Safety Level or BSL.
Laboratory facilities that handle infectious agents are categorized by the Biological Safety Level (BSL) that corresponds to the risk level of the pathogens being handled. BSL-3 Laboratories are designated for “indigenous or exotic agents that may cause serious or potentially lethal disease through the inhalation route of exposure”
Introduction to Class III Biological Safety Cabinets The Class III Biological Safety Cabinet, also referred to as a Class III BSC, is designed to provide the highest level of containment when working with hazardous materials. These gas-tight enclosures protect the operator, the environment as well as the work in progress.
The Compounding Aseptic Containment Isolator utilizes HEPA (High Efficiency Particulate Air) filters to provide the highest level of operator and product protection. The supply HEPA filter provides laminar flow air, which bathes the entire work area.
Compounding Aseptic Isolators provide a comprehensive system that ensures both safety to personnel as well as sterility to the product throughout the compounding processes. Compounding isolators utilize an ergonomic glove system that provides complete containment within the Compounding Aseptic Isolator while manipulating sterile compounds.
The new USP Chapter 800 will provide best practices for all processes related to hazardous drugs (HDs) in healthcare settings. The chapter details the requirements for all aspects of handling hazardous drugs such as storage, mixing, preparing, compounding, dispensing and administration. Chapter 800 provides standards and guidelines for protecting patients, health-system personnel and the environment.
Hospital pharmacies and other compounding facilities often process radiopharmaceuticals. These radioactive materials can be used for therapeutic applications but are most commonly utilized for diagnostic procedures. The radiopharmacy provides these specialized preparations for use in nuclear medicine. Pharmacists that handle radiopharmaceuticals are also referred to as Nuclear Pharmacists or Radiopharmacists.
Worldwide, millions of people are employed in laboratory settings. For example in the United States, according to OSHA, there are more than 500,000 lab employees. Lab environments present a variety of hazards. Laboratory safety equipment is fundamental in providing safe conditions for laboratorians and other staff.
Clean Air Benches Provide an Ultra-Clean Working Environment Laminar Flow Hoods provide a sterile working environment. These hoods, also called clean benches, allow for the handling of materials or any critical process that must be protected from outside contamination.
Mobile Laboratories are now deployed for a wide range of public health and biosecurity applications. These mobile labs provide bio-containment for regions that were previously inaccessible or for operations that require quick mobilization of laboratory resources. Mobile labs have long been in use for low-risk or non-critical applications.
Modular pharmaceutical and biopharmaceutical cleanroom production facilities are complete turnkey units that are designed, engineered and manufactured off-site. Upon completion, these modules are factory acceptance tested prior to being shipped for final installation. This assures that upon delivery, all critical systems are precisely configured, compliant and fully operational.
Pharmacy compounding equipment must provide the product, patient and personnel protection that that is required while compounding sterile preparations. Germfree’s Containment Isolators provide the full range of protection and all specifications to meet USP 797 regulations in the hospital pharmacy or cleanroom.