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Class III Biosafety Cabinet
Protection Type: Sample Protection
Industries: Biocontainment
Class III Biosafety Cabinet (BSC) as defined by the CDC/NIH publication, “Biosafety in Microbiological and Biomedical Laboratories” 6th Ed. (BMBL).
- Stainless Steel Construction
- Ergonomic viewing window
- Stainless steel gloveports
- Static, double-door airlock
Ensuring Safe Handling of High-Risk Biological Agents
Gloveboxes show up everywhere, biotechnology, biomedical research, nuclear, defense, pharmaceutical, semiconductor, and chemical work all rely on them. Ours earn a more specific name the moment the work turns dangerous.
When a glovebox is built to handle pathogens or support microbiological research, it’s a Class III Biosafety Cabinet (BSC), also called a Class 3 BSC, built to contain high-risk biological agents to the standard set by the Biosafety in Microbiological and Biomedical Laboratories (BMBL).
Suitability
Designed to meet the needs of multiple applications, the Class III Biosafety Cabinet (BSC), also known as a Class 3 BSC, is ideal for a wide range of industries and facilities.
Class III Biosafety Cabinet Applications
Specifications
Overall dimensions
| Model | Width | Depth | Height |
|---|---|---|---|
| SEA-3 (2 Glove) | 60.25" / 1531mm | 24.75" / 629mm | 76.375" / 1940mm |
| SEA-4 (3 Glove) | 72.25" / 1836mm | 24.75" / 629mm | 76.375" / 1940mm |
| SEA-6 (4 Glove) | 95.125" / 2417mm | 24.75" / 629mm | 76.375" / 1940mm |
Work area dimensions
| Model | Width | Depth | Height |
|---|---|---|---|
| SEA-3 (2 Glove) | 42" / 1067mm | 21.75" / 553mm | 29.25" / 743mm |
| SEA-4 (3 Glove) | 54" / 1372mm | 22" / 559mm | 29.25" / 743mm |
| SEA-6 (4 Glove) | 78.125" / 1985mm | 22" / 559mm | 29.25" / 743mm |
Filtration
Single Inlet / Double Exhaust HEPA Filters: Rated at 99.99% efficacy for particles to 0.3μ in diameter. Filters are sealed to the SEA with gasketed stainless frames designed for in-situ testing. Sanitary shut-off valves on both inlet and exhaust for a leak-tight interior.
Construction
All welded 10-16ga. type 304 and 316L (2.46 mm thick ISO 3406 Type A4) stainless steel (SS). Interior coved corners and radius bends for easy cleanup and spill containment. All SS surfaces are polished to a pharmaceutical grade (#4) fi nish for easy cleaning and decon. Included leveling all welded SS 36” (915mm) stand.
Ergonomics
Ergonomic viewing window: 3/8” (9.5mm) thick clear polycarbonate window with chemical resistant coating. Window is sealed to the glovebox with single-piece, water-jet cut silicone gasket. Viewing window is sloped at a nominal 5°-7° angle for ergonomics and comfort.
Safety
Static, double-door airlock: Doors are interlocked, preventing both doors from being opened simultaneously.
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Related resources
Germfree Standard Class 3 Glovebox User Manual
Frequently Asked Questions
What is a Class III biosafety cabinet (BSC)?
A Class III biosafety cabinet (BSC), also called a Class 3 BSC, is a gas-tight, glovebox-style enclosure that provides the highest level of personnel and environmental protection for handling high-risk biological agents, built to comply with Biosafety in Microbiological and Biomedical Laboratories (BMBL) specifications.
What is the difference between a Class III and a Class II biosafety cabinet?
A Class III BSC is a fully enclosed, gas-tight glovebox with no open front, operators access the work area only through attached gloves, providing maximum containment for the highest-risk agents. Class II cabinets (Types A2 and B2) have an open front with inward airflow protection and suit lower-risk biological work.
What standards does a Class III biosafety cabinet meet?
Germfree’s Class III biosafety cabinets are built to comply with the Biosafety in Microbiological and Biomedical Laboratories (BMBL) specifications for high-risk biological agent containment.
What is a Class III BSC used for?
Class III biosafety cabinets support applications including gene therapy, viral vector production, vaccine development, aerobiology, biosafety and biosecurity work, and disease response and surveillance, typically within mobile or modular biocontainment facilities.
What accessories are available for a Class III biosafety cabinet?
Available accessories include customizable pass-through airlocks (with windows, trays, gloveports, interlocks, HEPA purge, and up to 4 doors), through-wall embeds with seamless bioseals, stainless steel transport containers, chemical dunk tanks, biosecurity options like cameras and security bars, and exhaust filtration systems.
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