Custom Restricted Access Barrier Systems
Many pharmaceutical applications require localized Restricted Access Barrier Systems within the cleanroom. RABS provide separation between personnel and product. These units offer many flexible options for aseptic processing when a Pharmaceutical Isolator is not required. Germfree designs, engineers and manufactures custom RABS to meet your specific demands
RABS mitigate the risk of contamination to sterile materials, containers, vials or surfaces that may come into contact with the product. This significantly enhances aseptic conditions as compared to conventional cleanroom operations.
Germfree’s RABS are custom manufactured for each biopharmaceutical application. They range in size, process-flow, and requirements for air filtration. While each model may vary, it is critical that the units are built to appropriate guidelines and standards. We also specialize in the integration of components with complex designs.
RABS Provide Critical Aseptic Processing Control
Germfree offers both Closed and Open RABS. A key consideration is the proper engineering of air handling and filtration systems. RABS are ideally suited for handling sterile, non-hazardous products. However, with enhanced containment and SOPS some applications that include materials with limited levels of toxicity can be processed in a properly designed Closed RABS.
Our Closed – Active RABS incorporate onboard unidirectional HEPA filtration that provides ISO 5 air to the critical zone. These units operate within a cleanroom environment with a minimum standard of ISO 7. An integrated entry system or MAL (Material Airlock) allows for aseptic transfer. Interlocking doors are utilized if a rare open-door intervention is required.
Biopharmaceutical applications that involve handling highly potent products, toxic APIs or dangerous pathogens are conducted in Pharmaceutical Containment Isolators.
Multiple-chamber Pharmaceutical RABS
Germfree offers multiple-chamber RABS that can also be combined with isolator lines. This allows you to separate your materials, processes and improve workflow. Filtration systems and airflow controls are configured to prevent cross contamination or provide containment between chambers. This facilitates the handling and transfer of materials between barrier systems and allows sterile products to remain under isolation.
Pharmaceutical RABS – Rigorous Engineering Standards and Features:
Pharmaceutical applications range significantly in their scope and requirements. Germfree has extensive experience in manufacturing custom barrier systems that meet the most stringent fabrication standards.
Streamlined Manufacturing ⎯ Germfree Completes your Project Faster
We have a proven track record of delivering advanced products. Our leading-edge fabrication technology, engineering team and subject-matter experts are all located on-site, in our US factory. We provide an efficient and collaborative design process and coordinate all logistics. From concept to completion, we deliver advanced solutions in an accelerated timeline.
Contact Germfree to discuss your specific application and requirements for Pharmaceutical RABS.