Vertical Laminar Flow Hoods

Pharmaceutical Unidirectional Airflow Cabinets

BVBI Series Vertical Laminar Flow Hoods

Germfree manufactures Laminar Flow Hoods for a range of biopharmaceutical applications. Our BVBI series of all-welded stainless steel, vertical clean air benches provide a high degree of localized control for critical aseptic processes and the handling of sterile products. HEPA-filtered air continuously bathes the work deck removing organisms and particulates 0.3 micron in size with an efficiency of 99.99%.

HEPA filters are positioned above the work surface, providing vertical, unidirectional airflow within the cabinet. This ensures a smooth and uninterrupted flow of optimal ‘First Air’ to the process area. Germfree’s BVBI has an extra deep work area, which allows for maximum utilization and ease of placement of instruments and components.

Advanced Control for Biopharmaceutical Aseptic Processes

Laminar Flow Hoods provide unidirectional, ultra-clean air to enhance sterile product processing. They are widely used in cGMP-compliant production areas, USP 797 cleanrooms and 503B facilities.

Germfree’s units are engineered to meet or exceed all advanced specifications for ISO 5 (Formerly Class 100) Laminar Flow Cabinets. These include: ISO 14644-1, USP 797, US Federal Standard 209E and IES Recommended Practices.

Optimal Design: The Laminar Flow Hood that Enhances your Cleanroom

Germfree’s BVBI Series is engineered to enhance both the performance of the cabinet as well as the overall airflow efficiency of the cleanroom. The air-return is positioned near the bottom of the unit. This bottom intake feature delivers two advantages when it is located in a cGMP-compliant or USP 797 cleanroom:

  • A well-designed ISO Class 5 Laminar Flow Hood contributes to the operations of a cleanroom in relation to required Air Changes Per Hour (ACPH). The BVBI provides an additional advantage by drawing in air located toward the floor. By filtering the room air with the highest potential particle count; the BVBI can augment overall cleanroom efficiency.
  • The low position of the bottom air-intake ensures that return air is not pulled from the fan-filter ceiling modules. This facilitates the smooth downward flow of HEPA-filtered air for other operations conducted near the hood. Our BVBI design promotes overall efficiency of the cleanroom.
  • Compounding Operations for Pharmaceutical Clinical Drug Trials

    Germfree’s BVBI Series of Laminar Flow Hoods are an effective platform for preparing non-hazardous Compounded Sterile Preparations (CSPs). The deep work area is ideal for compounding and provides increased flexibility when using automated compounding devices. The units are constructed from all welded stainless steel with a pharmaceutical grade finish to ensure durability and ease of cleaning. 316L stainless steel is available.

    The BVBI features a SpillGuard along the back of the work deck. The fluorescent light housing is externally mounted for optimal lighting. The acrylic side panels allow for additional ambient light to enhance visibility.

    Read more about Validation Services offered by Germfree.

    Laminar Flow Workstations are designed to protect the product from airborne particulates in the ambient air. Personnel and the environment are not protected from materials located in the hood. The BVBI should not be used with biohazardous materials, toxins, anticancer agents, radionuclides, or hazardous chemicals. GERMFREE manufactures complete lines of Biological Safety Cabinets, Pharmaceutical Isolators, Fume Capture Systems and other containment equipment to protect personnel and the environment as well as the product.

    Germfree’s BVBI Series of Vertical Unidirectional Airflow Cabinets provide a wide range of solutions for biopharmaceutical aseptic processing.
    Contact Germfree about your specific sterile product requirements.

    Germfree also designs and manufactures Custom Laminar Flow Equipment and Downflow Booths.

    Product Specifications

    Overall Dimensions:
    • BVBI-3SSRX: 36 ⅛” wide ・ 38″ deep ・ 76 ¼” high (air duct is removable to reduce depth to 35 ⅛”)
    • BVBI-4SSRX: 49 ¼” wide ・ 38″ deep ・ 76 ¼” high
    • BVBI-6SSRX: 73″ wide ・ 38″ deep ・ 76 ¼” high
    • BVBI-8SSRX: 96 ⅞” wide ・ 38″ deep ・ 76 ¼” high
    Work Area Dimensions:
    • BVBI-3SSRX: 33 ⅛” wide ・ 28 ½” deep ・ 30 ¾” high
    • BVBI-4SSRX: 45 ¼” wide ・ 28 ½” deep ・ 30 ¾” high
    • BVBI-6SSRX: 69 ¼” wide ・ 28 ½” deep ・ 30 ¾” high
    • BVBI-8SSRX: 93 ⅛” wide ・ 28 ½” deep ・ 30 ¾” high


  • All stainless steel welded construction
  • 16 gauge stainless steel work deck is 36″ from the floor and reinforced to support 300+ pounds
  • Frame is 1 ½” square stainless steel tubing with legs that terminate with heavy-duty, cleanroom-grade locking casters
  • Side panels are stainless steel framed ¼” acrylic
  • High capacity motor/blower system with speed control to extend the life of the HEPA filter
  • Cleanroom-compatible pre-filter increases the life of the front loading HEPA filter while reducing particulates inside the cleanroom
  • Filter screen panel is removable for easy cleaning
  • Front mounted, external fluorescent lighting
  • 6″ demarcation line marked inside work area
  • 1″ stainless steel, adjustable I.V. bar with hooks
  • Separate lighted power ON/OFF indicator switches for blower and lighting
  • Electrical is 115 Volt, 60 Hz (220/50-60 Hz also available)
  • Ten foot power cord with molded grounded plug
  • ACCESSORIES: BVBI Laminar Flow Hood

    • Drawers Under Workdeck can be Mounted on Right, Left or Both Sides
    • Programmable Electrical Stand Height Adjustment
    • Stainless Steel Table – Custom sizes built to your specifications
    • Bin Cart
    • Duplex Electrical Outlet Installed In Work Area
    • Stopcock for Air, Gas or Vacuum
    • 8″ Deep Perforated Shelf
    • Sealed Data Port – Passage of 4 cables possible with individual adjustable diameters between 0.16″- 01/27″
    • Ergonomic Task Chair: Anti-Bacterial, Anti-Microbial Vinyl Covering
      Available Colors Include: Charcoal ・ Wine ・ Teal ・ Navy ・ Black

    Laminar Flow Hood Diagrams

    Please contact us for the diagrams of the specific model you are interested in.


    Contact Us

    Four Sunshine Blvd
    Ormond Beach, Florida 32174
    +1 386-265-4360