bioGO 53’ BSL-2+ Mobile Biocontainment Laboratory

Germfree’s bioGO Mobile Biocontainment Laboratories offer the ideal solution for providing surge capacity for laboratory services during periods of emergency. By utilizing a fully equipped, turnkey, Mobile Biocontainment Laboratory, facilities are able to rapidly increase their volume without sacrificing capabilities. Each mobile facility is engineered and constructed to meet or exceed the CDC NIH BMBL guidelines for BSL-2 laboratories and the World Health Organization (WHO) guidelines for BSL3 laboratories.

Germfree has been manufacturing innovative laboratory solutions for nearly six decades. Our mobile and modular biocontainment units deliver critical laboratory capacity in the US and throughout the world.

Germfree is the only manufacturer that provides a single-source, OEM solution for both the laboratory and all critical containment equipment. Our leadingedge engineering teams and subject-matter experts are located at our 173,000ft2 US manufacturing plant. Germfree’s turnkey mobile and modular units meet the most stringent bio-containment requirements and provide critical infrastructure for global health security.

Application

Germfree’s bioGO Mobile Biocontainment Laboratories are turnkey Biocontainment Facilities suited for immediate deployment within the continental United States. Applications include:

  • Emergency Disease Surveillance
  • Temporary Laboratory Space during facility down time
  • Laboratory Swing Space
  • Any application where microbiological containment laboratory space is required

bioGO Laboratories are designed to be powered from shore power and are equipped with an automatic transfer switch for integration to locally available generators to provide redundancy in case of power outages or fluctuations.

Features

Advanced Design and Engineering bioGO Biocontainment Laboratories comply with the NIH CDC Biosafety in Microbiological and Biomedical Laboratories (BMBL) 5th edition guidelines. Standard Enhancement such as anterooms, directional airflow, HEPA filtered supply air and HEPA filtered exhaust air provide added safety for the operators, samples, and the environment. These enhancements allow the laboratory to meet the World Health Organization (WHO) Biosafety Level 3.

Flexibility of Operations Our mobile containment laboratories are designed by a team of biocontainment experts to provide the optimal safety for the handling of biologically contaminated materials. This allows the facility to be effectively utilized for manipulating samples required to be handled in a containment laboratory environment.

Efficient Workflow Germfree’s bioGO Mobile Biocontainment Laboratories are engineered and equipped for the most efficient workflow. The facility is divided into designated work zones. Each zone provides HEPA filtered supply air and the primary containment equipment required for a safe sample flow throughout the laboratory process. Additionally, we strategically place stainless steel workstations, transfer airlocks, storage and supply areas, gowning benches, and staging tables.

Enhanced Ergonomics HEPA Filtered sample transfer airlocks centrally located in the Laboratory Command Center allow for samples to be processed into the laboratory while maintaining robust Chain of Custody Procedures.

Layout

Germfree’s bioGO Mobile Biocontainment Laboratories are designed with 5 Distinct Work Zones:

BSL-2 Enhanced” Laboratory: This “BSL-2 Enhanced” Laboratory area exceeds BMBL 5th edition Laboratory Facility guidelines as well as World Health Organization (WHO) guidelines for BSL-3 laboratories. The room air is both supplied and externally exhausted through HEPA filters. The room is equipped with two (2) Class II, Type A2 Biological Safety Cabinets to protect the product and personnel. One of the Class II Type A2 Biological Safety Cabinets is exhausted to the exterior through a HEPA Filter in case solvents are required for processing samples.

Ample storage space is provided by the custom casework as well as an integrated refrigerator and freezer. All casework is stainless steel with seamless welds, coved corners and radiused edges and is compatible with all standard gas and vapor decontamination systems.

BSL-2 Laboratory (PCR Prep): This BSL-2 Laboratory area exceeds BMBL 5th edition Laboratory Facility guidelines. The room is supplied with HEPA filtered air and the return air is HEPA filtered before being recirculated to other areas of the laboratory. Ample storage space is provided by the custom casework as well as an integrated refrigerator and freezer. All casework is stainless steel with seamless welds, coved corners and radiused edges and is compatible with all standard gas and vapor decontamination systems.

Anterooms 1 and 2: These rooms serve as an air brake to the trailer exterior and as a space for personnel to don their Personal Protective Equipment (PPE). The area is equipped with shelves for storing PPE, a hand washing sink and a gowning bench. The anteroom is maintained at positive pressure relative to the command center to provide an additional barrier to the air cascading into the BSL-2 laboratories. Pressure gauges at each door display room pressures, and have alarms to indicate unsafe conditions due to changes in the differential pressures between the rooms. All interior doors can be operated hands-free. Interlocks prevent both anteroom doors from being open simultaneously.

Laboratory Command Center: The Laboratory Command Center serves as the main entrance to the Mobile Biocontainment Laboratory and the main entrance door is equipped with the proper security for your application.

Construction Specifications

Germfree’s mobile biocontainment laboratories are designed to be exceptionally durable and easily cleanable. To achieve this, only the highest grade, cleanroom-compatible materials are used in the facility’s construction.

The interior walls are Arcoplast, a high performance composite that provides a seamless interior suitable for frequent wash-downs with sanitizing agents as well as gas bio-decontamination.

The floor is seamless Armstrong Medintech® vinyl, coved up the walls for ease-of-cleaning.

All work surfaces are seamless stainless steel with casework designed for gas and vapor phase decontamination. Surfaces are coved for easy spill cleanup and sanitization. Edges are rounded and polished to avoid snagging Personal Protective Equipment (PPE).

Mechanical Specifications

A heating, ventilation and air conditioning (HVAC) system is installed in the bioGO facility. The HVAC system is engineered to maintain a comfortable working temperature and humidity, and provides an inward flow of air into the BSL-2 laboratories. In the “BSL-2 Enhanced” Laboratory, the mechanical ventilation also prevents recirculation to spaces outside of the laboratory. The variable capacity, 11 Ton HVAC system is designed for the rigors of a fully exhausted “BSL-2 Enhanced” Laboratory in a package that has been proven to handle the challenges of a mobile platform.

Electrical Specifications

Connections for utility power and/or auxiliary generator inputs are provided via transfer switch. Diesel electric generator packages are optionally available and can be supplied by local equipment rental companies.

65kVA @208V, 3PH, 60Hz, 300A

  • Single point connection
  • Shore power inputs are provided

Plumbing Specifications

The plumbing system includes an on-board fresh water tank and an on-demand electric water pump to provide running water for the sinks. The capacity of the laboratory water tank is supplemented by a connection to a water utility tap. The fresh water tank is equipped with a low- level monitor.
A gray water tank is designed to be gravity drained. The laboratory will arrive completely plumbed, ready for connection to water supply and drain lines. The gray water tank is equipped with a high-level monitor.

  • (2) Stainless Steel Sinks, one in each anteroom
    • Includes emergency eyewash
    • 86 Gal on Board fresh water tank
      • Compatibility for connection to a water utility tap
    • 2.4 kW on-demand electric water pump
    • (2) 55-Gal gray water tanks
    • Gravity drained or storage for batch dumping
    • PEX supply and CPVC drain lines
    • Single Point of connection

Controls, Communications & Recording Systems

Communication Ports (12) Data ports are provided for network instruments, computer workstations and printers. Cables are run in shielded chases to a patch panel in the anteroom. Telephone port is provided in the Laboratory Command Center. Also included are:

  • Intercom System
  • Fire / Burglar System
  • BMS – Environmental Monitoring

Cameras and Monitors

Digital video cameras and a digital video recorder (DVR) provide perimeter security. Interior and exterior cameras provide live local video.
• CCTV system (8 cameras, DVR capable of recording 30 days of video)

Data / Phone Network

  • All data terminated into a patch panel in the command center
  • Computer and printer provided by end user
  • Data rack can support customer supplied switch
  • Cables in shielded chases
  • Telephone port will be provided in the Laboratory Command Center
  • Keyless entry main door

Testing & Quality Control

Germfree’s bioGO Quality Process is designed to evaluate performance as well as fit and finish of every system on our mobile platform. Evaluation and testing is conducted on all components and aspects of the facility.

Germfree’s Quality Control Team employs a checklist- based system during a rigorous trial period. All systems are thoroughly vetted and documented in real world conditions before the bioGO is allowed to leave our manufacturing facility.

Germfree’s commitment is to provide a complete, standalone facility with zero defects, ready and installed with complete confidence at our customer’s site.

Installation

Prior to delivery of the bioGO Mobile Facility, Germfree’s service department will work with you to determine what site work needs to be completed before installation can occur.

Pre-installation Consultation can include:

  • Location of the unit
  • Power supply
  • Data cables and integration
  • Fresh/waste water connections

Options: Germfree site visit for installation consultation.
Germfree technician/s will be on-site after delivery to assist with installation, setup, and to provide training on the startup and daily operation of the facility.

Cleaning & Bio-decontamination

bioGO Mobile Facilities receive a thorough, professional cleaning before they are deployed. Germfree has validated a bio-decontamination process that can be performed prior to shipping or on location that consists of triple cleaning followed by decontamination via vaporized / ionized hydrogen peroxide (VHP/IHP).

Triple Clean: Germfree’s process involves three separate, consecutive cleanings of the facility. Each pass involves a thorough wipe down of all surfaces. The first application uses a germicidal detergent with the second and third applications using a sporicidal agent. PECs and casework are wiped down with a 70% IPA following each cleaning.

VHP / IHP: Germfree’s validated bio-decontamination process uses either vaporized hydrogen peroxide (VHP) or ionized hydrogen peroxide (IHP).

Documentation

Each mobile laboratory is delivered with a full set of asbuilt drawings. Additional documentation, if necessary, can be requested from your project manager.

Standards & Codes

Germfree’s bioGO Mobile Biocontainment Laboratories meet or exceed the requirements of the CDC NIH BMBL 5th edition for BSL-2 Laboratories. Via enhancements beyond BMBL requirements, the bioGO Mobile Biocontainment Laboratory units comply with the WHO Laboratory Biosafety Manual for BSL-3 laboratories.

Additionally, Germfree’s bioGO Mobile Biocontainment Laboratories meet ISO 7 cleanroom requirements according to ISO 14644 by incorporating fan powered HEPA terminal units with low wall air returns. The units are engineered for precise HVAC, airflow, air pressure, balance strategies, and proper positioning of primary engineering controls within the laboratory.

Project Management

A dedicated project manager will oversee all aspects of your laboratory purchase from order through delivery. In so doing, it is possible to guarantee a seamless transition into your bioGO® Mobile Biocontainment Laboratory.

Equipment

Germfree’s bioGO Mobile Biocontainment Laboratories are delivered fully-equipped for ready for on-site commissioning. The standard configuration consists of:

BSL-2 Laboratory (PCR Prep)

  • Custom casework provides ample storage space
  • Standard laboratory refrigerator
  • Standard laboratory freezer
  • The preparation areas consist of stainless steel countertops with seamless welds, coved corners and radiused edges

“BSL-2 Enhanced” Laboratory

  • Two (2) Class II Type A Biosafety Cabinets
    • Model BBF-3SSRX
    • Model BBF-4SSRX
    • Outer cabinet and work surface are welded stainless steel with a #4 pharmaceutical grade finish
    • Front lifting viewing panel is easily removed and is gasketed to provide a proper seal when in place
    • Ergonomic front panel of the biological safety cabinet is concave permitting operator to lean into work area, enhancing user comfort
    • High capacity motor/blower system with speed control to extend the life of the HEPA filter
    • Supply and exhaust HEPA filters are parallel to work area and each other to prevent turbulence
    • Removable stainless steel work tray and tray supports facilitate easy clean up of the biological safety cabinet Fluorescent lights are externally mounted to minimize heat build-up
    • Separate lighted power ON/OFF indicator switches for blower and lighting
    • Electrical is 115 Volt, 60 Hz (220/50-60 Hz also available)
    • Ten foot power cord with molded grounded plug
    • Constructed to allow for optional outside venting of exhaust air from the biosafety cabinet
  • Custom casework provides ample storage space
  • Standard laboratory refrigerator
  • Standard laboratory freezer
  • Stand-up autoclave
  • The preparation areas consist of stainless steel countertops with seamless welds, coved corners and radiused edges

Laboratory Command Center

  • Two material pass boxes including (1) with HEPA-purge pass-through connecting the Command Center and the “BSL-2 Enhanced” Laboratory
    • Allows the transfer of materials from either of the laboratories into the Laboratory Command Center or vice-versa while maintaining containment
    • Interlocked doors assure that the airlock is never open on both sides simultaneously
    • HEPA-purge cycle removes particulates within the airlock, achieving ISO Class 5 conditions before the materials are removed
  • Stainless steel countertops with seamless welds, coved corners and radiused edges
  • Stainless steel casework
  • Security, Data and Environmental Monitoring are all accessible from the office area (see related sections)

Anterooms

  • Shelves for storing PPE
  • Stainless steel hand washing sink
  • Gowning bench

Quality Statement

Accountability: We will deliver our products on time, as promised, and free from defects.

Ownership: We will strive to exceed expectations at every level and we will work to make sure that each customer is satisfied with the service that they receive.

Longevity: All of our products are constructed from the highest quality materials and are designed to operate reliably for decades. We stand behind our work and take pride in our superior craftsmanship.

Our Company

Germfree has been a leading innovator in aseptic control and isolation systems since 1962.

We design and manufacture a diverse range of equipment and facilities for life science applications.

Our systems are integral to critical processes across many sectors. We specialize in complex projects and custom applications that serve the rigorous demands of our clients. Our high-specification bioGO Modular Facilities operate across the world, and are sustainable as permanent facilities in remote regions with harsh conditions

Contact Us

GERMFREE
Four Sunshine Blvd
Ormond Beach, Florida 32174
USA
+1 386-265-4360
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