When it comes to designing and constructing a cleanroom, there are a variety of options available, each with their own pros and cons. The four most common construction methods are stick-built, modular panels, prefabricated modules, and mobile cleanrooms on wheels. The choice of construction method will depend on various factors, including the application, environment, budget, project complexity, and timeline.

Prefabricated Offsite Built Modules, also known as prefab modules, are self-contained, pre-built cleanroom units that are constructed offsite in a controlled environment. This results in faster construction times, reduced contamination risks, and greater flexibility. Prefab modules can be customized to specific size, shape, and configuration requirements, and they can accommodate various levels of cleanliness. The downsides are higher initial costs for larger cleanroom applications and limited scalability for projects greater than 150,000 sq. ft.

Stick-built construction involves building the cleanroom on-site using traditional construction materials and methods. This option provides greater flexibility in design and customization and can be cost-effective for smaller cleanroom applications. However, stick-built construction takes longer, is heavily reliant on architectural engineering firms and subcontractors, and has a higher risk of contamination during construction.

Modular panels are pre-fabricated panels that are assembled on-site to create a cleanroom. They can be made from materials such as steel, aluminum, or plastic and are customizable to specific size, shape, and configuration requirements. Modular panels are scalable and may require more subcontractor work than other methods during the installation of prefabricated wall and ceiling panels.

Mobile cleanrooms on wheels are self-contained, portable units that can be easily transported and deployed on-site. They are ideal for short-term applications, such as distributed manufacturing, pharmacy compounding during renovations, emergency response, or clinical scale manufacturing. Mobile cleanrooms can be customized and quickly set up, but they may not suitable for long-term or permanent applications, are typically smaller, and can have space constraints.

The decision on which cleanroom construction option to choose will depend on several factors, including the application, environment, budget, and timeline. For example, a mobile cleanroom may be the best option for short-term clinical scale manufacturing, while a prefab or modular panel construction may be more suitable for long-term manufacturing or research applications. Stick-built construction may be more cost-effective for larger manufacturing facilities greater than 150,000 sq. ft., while prefab or modular panel construction may have higher initial costs but be more cost-effective in the long run.

In conclusion, selecting the right cleanroom construction option is essential for the success of any cleanroom project. By carefully considering various factors and consulting with cleanroom experts, facility owners can choose the construction option that best meets their needs and ensures the project’s success.