Application

mRNA

Revolution in medicine: mRNA technology unlocks transformative potential for disease treatment

Revolutionizing global mRNA production: Germfree's innovative cleanrooms drive manufacturing success

Cleanroom requirements for mRNA manufacturing encompass stringent particle control, temperature and humidity management, solvent management and robust contamination prevention strategies. As a result, Germfree’s advanced cleanroom solutions address these challenges, ensuring seamless equipment integration, process adaptability, and compliance with regulatory standards. Our tailored mobile and modular facilities support the emerging trend for localized vaccine production, empowering biopharmaceutical companies to harness the transformative potential of mRNA technology in a rapidly advancing field, and ultimately contributing to global immunization efforts.

Facilities and Equipment for mRNA Manufacturing

Select from a number of application-ready layouts & equipment. If these do not meet your needs, reach out and learn more about our custom solutions.

Mobile

bioGO^®: Mobile cGMP Cleanrooms for mRNA Manufacturing

The bioGO® cGMP Mobile Cleanroom trailer meets urgent biopharma capacity needs, adaptable across processes from cell therapy to sterile fill manufacturing, and built for clinical phase or point-of-care work. It’s backed by full-service support: design, fabrication, validation, and maintenance.

Germfree engineers and operates the platform to meet FDA cGMP requirements and industry best practice, giving biopharma manufacturers a flexible, compliant way to add capacity fast.

Learn more about our mobile facilities

Germfree has deployed more than 100 cGMP and USP <797>/<800> mobile cleanrooms globally since 2015
Integrated biosafety cabinets, laminar flow hoods, pass-throughs, gowning benches and 100% stainless steel casework
Enhanced particulate control and cGMP compliance by design, ISO 7/8 Grade B, C and D
Supported by comprehensive services, including 24 hour/ 7 day a week service support , remote monitoring and preventative maintenance
Rapid deployment in weeks not months; gain access to the clinic sooner
Available for sale or lease to maximize capital spend

Mobile cGMP Cleanrooms

Germfree’s Mobile cGMP Cleanroom platform supports aseptic processing needs with a flexible, rapidly deployable design.

Key applications:

Cell Therapy

Gene Therapy

Aseptic Filling

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Modular

Modular cGMP Cleanrooms for mRNA Manufacturing

Germfree’s prefabricated modular cleanroom facilities support advanced therapy and pharmaceutical production, with layout options and mechanical space configurations for a free-standing facility or one inside a shell building.

Design, project management, supply chain, commissioning and qualification, and maintenance are handled as one service, start to finish. These facilities are built for flexibility, reliability, and compliance in biopharmaceutical manufacturing.

Learn more about our modular facilities

Onsite in ~ 8 Months for standard platforms
Compliant: US & EU cGMP – BSL2 -BSL3, ISO14644
Flexible layout configurations based on standard platform technology
High quality construction by design minimizes risk of contamination
Provided turnkey with comprehensive services, including commissioning and qualification, 24 hour/ 7 day a week service support, remote monitoring and preventative maintenance
Can be combined with pharmaceutical isolators, RABs, Biosafety cabinets, laminar flow hoods, passthroughs, gowning benches and 100% stainless steel casework
Available for sale or lease

Modular cGMP Cleanrooms

Germfree cGMP Modular Cleanroom facilities support both cGMP and cGMP/BSL2 production.

Key applications:

Aseptic Filling

CGT Manufacturing

Viral Vectors

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Equipment

Innovative Aseptic Processing Equipment and PECs

Germfree’s standard and custom equipment line was the foundation of our company over 60 years ago. We’ve been continuously innovating this equipment to create a line of primary engineering controls (PECs), refined over six decades. Our PECs are 100% stainless steel, with intuitive ergonomic design and the ability to handle both hazardous and non-hazardous materials. Plus, all of our equipment has a long service life spanning decades.

Check out our range of Pharmaceutical Isolators and Restricted Access Barrier Systems, Laminar Flow Workstations, Biological Safety Cabinets (BSCs), Compounding Aseptic Isolators (CAIs), Compounding Aseptic Containment Isolators (CACIs), Powder Hoods, and Material Pass Throughs to see how we can meet your needs. Trust Germfree for top-quality equipment that’s built to last.

Standard Biosafety Cabinets and Laminar Flow Equipment ships fast
NSF/ANSI49 Options Available
Innovative touch control interface on some models
100% 304 and 316 L Stainless Steel Construction
Modular or mobile facility integration
Durable and easy to clean, backed by a service life spanning decades

All EQT- Biopharmaceutical Isolators & RABS EQT-Class II Type A2 BSC EQT-Class II Type B2 BSC EQT-Vertical Laminar Airflow Workstation EQT-Horizontal Laminar Airflow Workstation EQT - 100% Stainless Steel Casework EQT-Pass-Through

Pharmaceutical Isolators

Germfree designs and manufactures cGMP-compliant pharmaceutical isolators in the USA, protecting products, personnel, and laboratory processes.

Smarthood™

Smarthood™ is our innovative solution that integrates essential peripherals like touchscreen PCs, cameras, scales, and printers directly into a clean, clutter-free hood, enhancing aseptic technique and streamlining your workflow.

Stainless Steel Laboratory Furniture

Germfree's 100% stainless steel laboratory furniture resists corrosion, rust, and bacterial growth, custom designed for your lab or cleanroom.

Frequently Asked Questions

Explore additional insights

What cleanroom requirements apply to mRNA manufacturing?

mRNA manufacturing requires stringent particle control, temperature and humidity management, solvent management, and robust contamination prevention strategies, along with seamless equipment integration and compliance with regulatory standards.

Does Germfree support localized vaccine production?

Yes — in fact, Germfree’s tailored mobile and modular facilities support the emerging trend for localized vaccine production, helping biopharmaceutical companies scale mRNA manufacturing.

What mobile cleanroom options are available for mRNA manufacturing?

The bioGO® cGMP Mobile Cleanroom trailer offers enhanced particulate control and cGMP compliance by design (ISO 7/8 Grade B, C and D), with rapid deployment in weeks rather than months, and is available for sale or lease.

Are modular cleanrooms available for mRNA manufacturing?

Yes. Germfree’s prefabricated modular cleanroom facilities support advanced therapy and pharmaceutical production processes, available as free-standing facilities or located in a shell building, and can be combined with pharmaceutical isolators, Restricted Access Barrier Systems, biosafety cabinets, laminar flow hoods, passthroughs, gowning benches, and stainless steel casework.

What equipment does Germfree offer for mRNA production processes?

Specifically, Germfree’s equipment line includes pharmaceutical isolators, Restricted Access Barrier Systems, laminar flow workstations, biological safety cabinets, compounding aseptic isolators and containment isolators, powder hoods, and material pass throughs.

Can Germfree’s cleanroom facilities support both cGMP and BSL-2 production?

Yes. Germfree cGMP Modular Cleanroom facilities are a turnkey platform solution that enable both cGMP and cGMP/BSL-2 production.

Talk to us about the right solution for your application

When your mission calls for something custom, we deliver.

Some environments can’t take a catalog answer: the one-of-a-kind containment lab, the facility that has to survive shipment by military aircraft, the compounding pharmacy that has to stand up overnight. Tell us the constraints, we’ll build around them.

Get started on yours