BIOCONTAINMENT SOLUTIONS

Class II Biosafety Equipment

Germfree is internationally recognized as a leading manufacturer of Class II Biological Safety Cabinets. Our Class II Gloveboxes provide containment for diverse research applications in advanced BSL-2 laboratories. Our Class II BSCs are engineered to exceedingly rigorous standards for work that requires the protection of operator or product. We specialize in custom integration of all laboratory components.

The Class II, Type A Laminar Flow Biological Safety Cabinet provides protection for the user, product and the environment from particulate and aerosol hazards. The work area of the biological safety cabinet is continuously bathed with positive pressure ISO 5/Class 100 HEPA-filtered air to protect the product from contamination while an inward airflow protects the user.

Trusted worldwide, the BBF Series (Class II, Type A) of Laminar Flow Biological Safety Cabinet are designed for the safe handling of low to moderate risk agents in laboratories and other settings. These biosafety cabinets eliminate cross-contamination and the accidental release of pathogenic microorganisms or carcinogenic aerosols and drugs to the outside atmosphere. Other applications for these biological safety cabinets include handling materials such as pollen, powders, allergens, dust, pathogen-free animals and plants. An integrated ISO 5/Class 100 HEPA filter removes organisms and particulates 0.3 micron in size with an efficiency of 99.99%. It is even more efficient for larger and smaller particles. The laminar flow principle consists of moving individual streams of unidirectional, ultra-clean air along parallel lines with minimal turbulence to protect product or personnel.

Class II hoods provide personnel, environmental, and product protection for a range of low- to moderate-risk materials. These biological safety cabinets are used in research, clinical, industrial, and pharmacy settings. With Class II cabinets, airflow is drawn into the front grille of the unit, providing personnel protection. In addition, the downward flow of HEPA-filtered air provides product protection by minimizing the chance of cross-contamination across the work surface of the hood. Exhaust air is passed through a certified HEPA filter to provide particulate filtration to protect the environment. For Class II, Type A1 and A2 BSCs, exhaust air may be recirculated to the laboratory or, alternatively, it may be discharged from the building via a canopy, or “thimble,” connected to the building’s exhaust. CDC regulation standards require exhaust air for Class II, Types B1 and B2 BSCs be discharged directly to the outdoors via a hard connection.

Germfree’s Biological Safety Cabinets are Constructed of All-Welded Stainless Steel With a Pharmaceutical Grade Finish.
The BBF Biological Safety Cabinet is constructed of quality all-welded stainless steel with a pharmaceutical grade finish. The fluorescent light housing is externally mounted to provide optimum lighting into the work area. The front viewing panel allows for additional ambient light and visibility into the work area and has a unique, recessed, contoured shape, which creates an aerodynamic flow pattern and allows the operator to lean into the work area. It is this combination that produces the protective barrier for the operator by containing hazardous materials within the biological safety cabinet. The viewing panel is hinged so it can be easily opened for cleaning and placement of larger objects into the work area. The stainless steel work tray can also be removed from the biological safety cabinet for ease of cleaning.

Approximately 70% of the air from each cycle is recirculated through the supply HEPA filter while the remaining air is discharged from the biological safety cabinet through the exhaust HEPA filter.

Our Biological Safety Cabinets are available with all-welded stainless steel stands for operation at a fixed sitting or standing work height. For further ergonomic considerations, adjustable stands are available with either manual or electric height adjustment. For additional information and available options for Germfree’s Biological Safety Cabinets please refer to the unit specification sheet.

The BBF Series of Vertical Laminar Flow Biosafety Cabinets passes the Biological Tracer Containment tests of the National Institutes of Health (NIH), the National Cancer Institute (NCI), and the National Sanitation Foundation (NSF). All units are NRTL listed with MET Labs to comply with UL 1262.

Operation as a Class II, Type A2 Biological Safety Cabinet

Our 3, 4, and 6-foot units are Class II, Type A2 Biological Safety Cabinets as required by USP <800>. External exhaust system to vent (duct) the remaining HEPA filtered air to the outside is possible by ordering a thimble transition piece. Consult with a Germfree Customer Service Representative for further details. Please see the following units for this option: BBF-3SSRX, BBF-4SSRX and BBF-6SSRX.

Standard Configurations

Explore our Standard Glovebox options

BBF-3-with-transition-no-bkgd-scaled-1.jpg

Class II Type A2 - BBF Series

The BBF Series (Class II, Type A2) of Laminar Flow Biological Safety Cabinet are designed for the safe handling of low to moderate risk agents in laboratories and other settings. These biosafety cabinets eliminate cross-contamination and the accidental release of pathogenic microorganisms or carcinogenic aerosols and drugs to the outside atmosphere.

BTE-3-with-Person-no-bkgd

Class II Type B2 - BTE Series

The BTE Series Class II, Type B2 Laminar Flow Total Exhaust BSC provides USP 797 & USP 800 compliant protection for the user and the product from gases/fumes, aerosols and particulate hazards. The work area is continuously bathed with positive pressure ISO 5/Class 100 HEPA-filtered air while creating a negative pressure airflow into the cabinet to provide user protection.

Class II Custom

Work with Germfree’s expert team to develop a solution that is specific to your unique laboratory requirements and overall application. Germfree’s Custom Class II BSC’s have been deployed around the world, for operation in laboratories, pharmacies, and research facilities.

CLASS II BIOSAFETY CABINETS

Class II Type A2

BBF SERIES

The BBF Series (Class II, Type A2) of Laminar Flow Biological Safety Cabinet are designed for the safe handling of low to moderate risk agents in laboratories and other settings. These biosafety cabinets eliminate cross-contamination and the accidental release of pathogenic microorganisms or carcinogenic aerosols and drugs to the outside atmosphere. Other applications for these biological safety cabinets include handling materials such as pollen, powders, allergens, dust, pathogen-free animals and plants.

Class II Type A2

The Class II, Type A2 Laminar Flow Biological Safety Cabinet provides protection for the user, product and the environment from particulate and aerosol hazards. The work area of the biological safety cabinet is continuously bathed with positive pressure ISO 5/Class 100 HEPA-filtered air to protect the product from contamination while an inward airflow protects the user. Approximately 70% of the air from each cycle is recirculated through the supply HEPA filter while the remaining air is discharged from the biosafety cabinet through the exhaust HEPA filter.

  • The BBF Series (Class II, Type A) of Laminar Flow Biological Safety Cabinet are designed for the safe handling of low to moderate risk agents in laboratories and other settings. These biosafety cabinets eliminate cross-contamination and the accidental release of pathogenic microorganisms or carcinogenic aerosols and drugs to the outside atmosphere. Other applications for these biological safety cabinets include handling materials such as pollen, powders, allergens, dust, pathogen-free animals and plants. Learn More.

Portable Class II

Decades of experience building equipment for a variety of high containment applications has positioned Germfree to deliver a right-sized solution for your application. Germfree's robust engineering team will work together through your assigned project manager to deliver a custom containment solution, built off decades of containment experience.

  • As a portable Class II, pharmacy, laboratory, and research functions can now be completed in a more diverse set of locations and circumstances. The Portable Class II leverages design excellence from Germfree’s standard line of fixed Class II BSC’s to deliver the ultimate portable solution.
Germfree Portable Class II Biosafety Cabinet

CLASS II BIOSAFETY CABINETS

Class II Type B2

BTE SERIES

The Class II, Type B2 Laminar Flow Biological Safety Cabinet provides protection for the user and the product from gases/fumes, aerosols and particulate hazards. The work area is continuously bathed with positive pressure ISO 5/Class 100 HEPA-filtered air while creating a negative pressure airflow into the cabinet to provide user protection. All of the air entering the hood is ducted/vented to the outside of the building.

Class II Type B2

The work area is bathed with a HEPA-filtered unidirectional (laminar) flow ISO 5/Class 100 air to protect the product. Further, the exhaust air is HEPA-filtered to protect the environment from particulate and aerosol hazards. This filter removes organisms and particulates 0.3 micron in size with an efficiency of 99.99%. The laminar flow principle consists of moving individual streams of unidirectional, ultra-clean air along parallel lines with minimal turbulence. This Class II, Type B2 Biological Safety Cabinet is a 100% Total Exhaust unit.

  • The BTE Series Class II, Type 2 Laminar Flow Total Exhaust BSC provides  USP 797 & USP 800 compliant protection for the user and the product from gases/fumes, aerosols and particulate hazards. The work area is continuously bathed with positive pressure ISO 5/Class 100 HEPA-filtered air while creating a negative pressure airflow into the cabinet to provide user protection. 

CLASS II BIOSAFETY CABINETS

Custom Class II

GERMFREE LABORATORIES, INC

Work with Germfree to create an application-specific solution the will revolutionize your process.

Optimized For Your Lab

While most of Germfree's standard BSC equipment suits the needs of pharmacies, labs and research facilities, some clients require custom-fit solutions. Germfree's engineering team is standing by to build off our standard equipment to create the solution for your specific application or needs.

  • Work with Germfree’s expert team to develop a solution that is specific to your unique laboratory requirements and overall application. Germfree’s Custom Class II BSC’s have been deployed around the world, for operation in laboratories, pharmacies, and research facilities.

Past Germfree Projects

Germfree consistently delivers exceptional cGMP compliant products around the globe. Browse the grid below to see a selection of relevant past projects:

Mobile Hospital Compounding Pharmacy
Mobile
The remodeling of an I.V. pharmacy presents a range of potentially difficult or costly challenges. During building renovations it is imperative that compounding operations are not interrupted or otherwise negatively impacted
USA
Microbiome Research Modular Cleanroom
Biopharma Projects
This BSL 2+ cGMP Modular Biocontainment Cleanroom Facility is made up of five (5) prefabricated modules (2,000 ft2 / 184 m2 gross area) and is housed within a renovated warehouse structure. The cleanroom is designed to comply with FDA and EU cGMP standards and utilizes a unidirectional process flow.
Alachua, FL
Mobile Viral Vector Production Facility
Biopharma Projects
This Mobile BSL-3 Viral Vector Production Facility is based on quantity 2 semi-trailer chassis (840 ft2 / 79 m2 gross area) and functions as a mobile cGMP cleanroom to facilitate Viral Vector Manufacturing (VVM).
Maryland, USA

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It is the dedication of the Germfree team that enables rapid deployment of critical infrastructure both to cutting edge research facilities and the front lines of global health security

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